(3aR,4R,5R,6aS)- 5-(benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-one

Base Information

Chemical Name:(3aR,4R,5R,6aS)- 5-(benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-one
CAS No.:208111-89-1
Molecular Formula:C24H23ClO6
Molecular Weight:442.89
Hs Code.:
Mol file:208111-89-1.mol

Synonyms:(3aR,4R,5R,6aS)- 5-(benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-one

Suppliers and Price of (3aR,4R,5R,6aS)- 5-(benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

TRC
[3aR,4R(1E,3S),5R,6aS]-5-Benzoyloxy-4-(3-hydroxy-4-phenoxy-1-buten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one
10mg
$ 165.00

Total 8 raw suppliers

Chemical Property of (3aR,4R,5R,6aS)- 5-(benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-one

Chemical Property:

Boiling Point:641.4±55.0 °C(Predicted)
PKA:13.32±0.20(Predicted)
PSA：82.06000
Density:1.36±0.1 g/cm3(Predicted)
LogP:3.81310

Purity/Quality:

98% ,99% , ^*data from raw suppliers

[3aR,4R(1E,3S),5R,6aS]-5-Benzoyloxy-4-(3-hydroxy-4-phenoxy-1-buten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3aR,4R,5R,6aS)- 5-(benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-one

There total 1 articles about (3aR,4R,5R,6aS)- 5-(benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 178454-81-4
[3aR,4R(1E),5R,6aS]-5-benzoyloxy-4-[4-(3-chlorophenoxy)-3-oxo-1-buten-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-one

: 208111-89-1
[3aR,4R(1E,3S),5R,6aS]-5-benzoyloxy-4-[4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-one

: 178272-82-7
[3aR,4R(1E,3R),5R,6aS]-5-benzoyloxy-4-[4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-one

Guidance literature:: With (+)-β-chlorodiisopinocampheylborane; In tetrahydrofuran; at 0 ℃;
DOI:10.1016/j.bmc.2004.04.034

Reference yield:

: 208111-89-1
[3aR,4R(1E,3S),5R,6aS]-5-benzoyloxy-4-[4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-one

: 208111-92-6
[3aR,4R(3R),5R,6aS]-4-[4-(3-chlorophenoxy)-3-fluorobutyl]-5-hydroxy-hexahydro-2H-cyclopenta[b]furan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / H₂ / Pd/C / ethyl acetate / atmospheric pressure

2: 33 percent / (diethylamino)sulfur trifluoride / CH₂Cl₂

3: 67 percent / K₃CO₃ / methanol

With diethylamino-sulfur trifluoride; hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; dichloromethane; ethyl acetate;
DOI:10.1016/j.bmc.2004.04.034

Reference yield:

: 208111-89-1
[3aR,4R(1E,3S),5R,6aS]-5-benzoyloxy-4-[4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-hexahydro-2H-cyclopenta[b]furan-2-one

: Benzoic acid (3aR,4R,5R,6aS)-4-[(E)-4-(3-chloro-phenoxy)-but-2-enyl]-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / H₂ / Pd/C / ethyl acetate / atmospheric pressure

2: (diethylamino)sulfur trifluoride / CH₂Cl₂

With diethylamino-sulfur trifluoride; hydrogen; palladium on activated charcoal; In dichloromethane; ethyl acetate;
DOI:10.1016/j.bmc.2004.04.034