12-AMino Minocycline

Base Information

• Chemical Name: 12-AMino Minocycline
• CAS No.: 864073-42-7
• Molecular Formula: C₂₃H₂₈N₄O₆
• Molecular Weight: 456.499
• Mol file: 864073-42-7.mol

Synonyms:12-AMino Minocycline;(4S,4aS,5aR,12aS)-12-AMino-4,7-bis(diMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12a-trihydroxy-1,11-dioxo-2-naphthacenecarboxaMide

Chemical Property of 12-AMino Minocycline

Chemical Property:

• PSA: 171.41000
• LogP: 1.43730
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

NLT 98% ^*data from raw suppliers

12-Amino minocycline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 12-AMino Minocycline is an impurity of Minocycline (M344800),it is used in the preparation of calpain inhibitors.

Technology Process of 12-AMino Minocycline

There total 1 articles about 12-AMino Minocycline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

minocycline Hydrochloride (13614-98-7) → [4S-(4a,12aα)]-12-amino-4,7-bis(dimethylamino)-3,10,12a-trihydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide (864073-42-7)

Guidance literature:

With ammonia; In ethanol; at 20 ℃; for 4h; Heating / reflux;

upstream raw materials:

minocycline Hydrochloride

Refernces