(2-methanesulfonyl-2-methyl-1-(2-(5-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carbonyl)propyl)carbamic acid methyl ester

Base Information

Chemical Name:(2-methanesulfonyl-2-methyl-1-(2-(5-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carbonyl)propyl)carbamic acid methyl ester
CAS No.:1256386-79-4
Molecular Formula:C₂₇H₃₉BN₄O₇S
Molecular Weight:574.506
Hs Code.:
Mol file:1256386-79-4.mol

(2-methanesulfonyl-2-methyl-1-(2-(5-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carbonyl)propyl)carbamic acid methyl ester

Synonyms:(2-methanesulfonyl-2-methyl-1-(2-(5-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carbonyl)propyl)carbamic acid methyl ester

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Chemical Property of (2-methanesulfonyl-2-methyl-1-(2-(5-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carbonyl)propyl)carbamic acid methyl ester

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

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Technology Process of (2-methanesulfonyl-2-methyl-1-(2-(5-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carbonyl)propyl)carbamic acid methyl ester

There total 3 articles about (2-methanesulfonyl-2-methyl-1-(2-(5-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carbonyl)propyl)carbamic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1007882-12-3
(S)-tert-butyl 2-(5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

: 1256386-80-7
2-methoxycarbonylamino-3-methanesulfonyl-3-methylbutyric acid

: 1256386-79-4
(2-methanesulfonyl-2-methyl-1-(2-(5-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carbonyl)propyl)carbamic acid methyl ester

Guidance literature:: (S)-tert-butyl 2-(5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate; With hydrogenchloride; In 1,4-dioxane; for 4h;

2-methoxycarbonylamino-3-methanesulfonyl-3-methylbutyric acid; With 4-methyl-morpholine; HATU; In N,N-dimethyl-formamide; for 18h;

Reference yield:

: 1007882-04-3
(S)-tert-butyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

: 1256386-79-4
(2-methanesulfonyl-2-methyl-1-(2-(5-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carbonyl)propyl)carbamic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium acetate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 16 h / 80 °C

2.1: hydrogenchloride / 1,4-dioxane / 4 h

2.2: 18 h

With hydrogenchloride; potassium acetate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane;

Reference yield:

: 73183-34-3
bis(pinacol)diborane

: 1256386-79-4
(2-methanesulfonyl-2-methyl-1-(2-(5-(4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carbonyl)propyl)carbamic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium acetate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 16 h / 80 °C

2.1: hydrogenchloride / 1,4-dioxane / 4 h

2.2: 18 h

With hydrogenchloride; potassium acetate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane;