(-)-3-Acetyl-4-(3-methyl-1-oxobutyl)-2,6(1H,3H)-pyridinedione

Base Information

Chemical Name:(-)-3-Acetyl-4-(3-methyl-1-oxobutyl)-2,6(1H,3H)-pyridinedione
CAS No.:30674-34-1
Molecular Formula:C₁₂H₁₅NO₄
Molecular Weight:237.255
Hs Code.:
Mol file:30674-34-1.mol

Synonyms:(-)-3-Acetyl-4-(3-methyl-1-oxobutyl)-2,6(1H,3H)-pyridinedione;Glutamycin

Suppliers and Price of (-)-3-Acetyl-4-(3-methyl-1-oxobutyl)-2,6(1H,3H)-pyridinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of (-)-3-Acetyl-4-(3-methyl-1-oxobutyl)-2,6(1H,3H)-pyridinedione

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (-)-3-Acetyl-4-(3-methyl-1-oxobutyl)-2,6(1H,3H)-pyridinedione

There total 19 articles about (-)-3-Acetyl-4-(3-methyl-1-oxobutyl)-2,6(1H,3H)-pyridinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: tert-butyl {(2RS,3RS)-2-[2-(2-methyl-1,3-dioxolan-2-yl)acetyl]-3-(3-methylbutanoyl)oxirane-2-carbonyl}carbamate

: 8,9-dihydroxy-8-isobutyl-2-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione

: 30674-34-1
6-methyl-2-(3-methyl-1-oxobutyl)-1-oxa-5-azaspiro[2.5]oct-6-ene-4,8-dione

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; at 20 ℃; for 0.166667h;
DOI:10.1016/j.bmcl.2019.03.034

Reference yield: 53.0%

: tert-butyl [(2RS,3RS)-2-(3-hydroxybut-2-enoyl)-3-(3-methylbutanoyl)oxirane-2-carbonyl]carbamate

: 30674-34-1
6-methyl-2-(3-methyl-1-oxobutyl)-1-oxa-5-azaspiro[2.5]oct-6-ene-4,8-dione

Guidance literature:: With dichloro bis(acetonitrile) palladium(II); In acetone; at 20 ℃; for 120h;
DOI:10.1002/anie.201602910

Reference yield: 19.0%

: tert-butyl {(2RS,3RS)-2-[2-(2-methyl-1,3-dioxolan-2-yl)acetyl]-3-(3-methylbutanoyl)oxirane-2-carbonyl}carbamate

: 205386-57-8
(±)-rubrobramide

: 8,9-dihydroxy-8-isobutyl-2-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione

: 30674-34-1
6-methyl-2-(3-methyl-1-oxobutyl)-1-oxa-5-azaspiro[2.5]oct-6-ene-4,8-dione

Guidance literature:: tert-butyl {(2RS,3RS)-2-[2-(2-methyl-1,3-dioxolan-2-yl)acetyl]-3-(3-methylbutanoyl)oxirane-2-carbonyl}carbamate; at 140 ℃; for 0.5h;

With toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 19h;
DOI:10.1016/j.bmcl.2019.03.034