3-(2-Morpholinoethylamino)-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide

Base Information

Chemical Name:3-(2-Morpholinoethylamino)-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide
CAS No.:86663-19-6
Molecular Formula:2BrH*C₁₇H₂₂N₄O₂
Molecular Weight:476.211
Hs Code.:
DSSTox Substance ID:DTXSID601007001
ChEMBL ID:CHEMBL1743703

Synonyms:SR 95082;3-(2-Morpholinoethylamino)-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide;3-((beta-Morpholinoethyl)amino)-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide;3-(5-Methyl-6-((2-(4-morpholinyl)ethyl)amino)-3-pyridazinyl)phenol dihydrobromide;Phenol, 3-(5-methyl-6-((2-(4-morpholinyl)ethyl)amino)-3-pyridazinyl)-, dihydrobromide;86663-19-6;CHEMBL1743703;DTXSID601007001;LS-104886;3-(5-Methyl-6-{[2-(morpholin-4-yl)ethyl]imino}-1,6-dihydropyridazin-3-yl)phenol--hydrogen bromide (1/2)

Suppliers and Price of 3-(2-Morpholinoethylamino)-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(2-Morpholinoethylamino)-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide

Chemical Property:

Vapor Pressure:1.23E-14mmHg at 25°C
Boiling Point:592.6°Cat760mmHg
Flash Point:312.2°C
Density:g/cm³
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:476.02455
Heavy Atom Count:25
Complexity:352

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC(=CC=C3)O.Br.Br

Technology Process of 3-(2-Morpholinoethylamino)-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide

There total 5 articles about 3-(2-Morpholinoethylamino)-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 118269-94-6
[6-(3-Methoxy-phenyl)-4-methyl-pyridazin-3-yl]-(2-morpholin-4-yl-ethyl)-amine; hydrochloride

: 86663-19-6
3-<(β-Morpholinoethyl)amino>-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide

Guidance literature:: With hydrogen bromide; In acetic acid; for 6h; Heating;
DOI:10.1021/jm00123a004

Reference yield:

: 60855-46-1
3-chloro-6-(3-methoxyphenyl)-4-methylpyridazine

: 86663-19-6
3-<(β-Morpholinoethyl)amino>-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide

Guidance literature:: Multi-step reaction with 2 steps

2: conc. aq. HBr / acetic acid / 6 h / Heating

With hydrogen bromide; In acetic acid;
DOI:10.1021/jm00123a004

Reference yield:

: 118270-06-7
6-(3-Methoxy-phenyl)-4-methyl-2H-pyridazin-3-one

: 86663-19-6
3-<(β-Morpholinoethyl)amino>-4-methyl-6-(3-hydroxyphenyl)pyridazine dihydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃ / 80 °C

3: conc. aq. HBr / acetic acid / 6 h / Heating

With hydrogen bromide; trichlorophosphate; In acetic acid;
DOI:10.1021/jm00123a004