Technology Process of 6-PHENYL-PYRAZINEMETHANOL
There total 9 articles about 6-PHENYL-PYRAZINEMETHANOL which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium hydrogencarbonate;
In
methanol;
for 1h;
Heating;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 51 percent / PCl5, POCl3 / 1 h / 140 °C / Heating; sealed tube
2: 18 percent / 90percent H2O2, maleic anhydride / CHCl3 / 1.) room temperature, overnight; 2.) reflux, 3 h
3: 95 percent / tetrakis(triphenylphosphine)palladium, sodium formate / dimethylformamide / 2 h / 100 °C
4: 45 percent / 1 h / Heating
5: 71 percent / 10percent KHCO3 / methanol / 1 h / Heating
With
maleic anhydride; tetrakis(triphenylphosphine) palladium(0); phosphorus pentachloride; dihydrogen peroxide; sodium formate; potassium hydrogencarbonate; trichlorophosphate;
In
methanol; chloroform; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 18 percent / 90percent H2O2, maleic anhydride / CHCl3 / 1.) room temperature, overnight; 2.) reflux, 3 h
2: 95 percent / tetrakis(triphenylphosphine)palladium, sodium formate / dimethylformamide / 2 h / 100 °C
3: 45 percent / 1 h / Heating
4: 71 percent / 10percent KHCO3 / methanol / 1 h / Heating
With
maleic anhydride; tetrakis(triphenylphosphine) palladium(0); dihydrogen peroxide; sodium formate; potassium hydrogencarbonate;
In
methanol; chloroform; N,N-dimethyl-formamide;
