27-Hydroxy-7-keto Cholesterol

Base Information

• Chemical Name: 27-Hydroxy-7-keto Cholesterol
• CAS No.: 148988-28-7
• Molecular Formula: C27H44O3
• Molecular Weight: 416.63646
• Mol file: 148988-28-7.mol

Synonyms:27-Hydroxy-7-keto Cholesterol;(3β)-3,26-Dihydroxycholest-5-en-7-one

Chemical Property of 27-Hydroxy-7-keto Cholesterol

Chemical Property:

• PSA: 57.53000
• LogP: 5.54010

Purity/Quality:

98% ^*data from raw suppliers

27-Hydroxy-7-ketoCholesterol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A cytostatic sterol for treatment of cancer and other conditions associated with rapidly growing cells. 27-Hydroxy-7-ketocholesterol is an alcohol derivative of 27-Carboxy-7-Ketocholesterol, which is a cytostatic sterol for treatment of cancer and other conditions associated with rapidly growing cells.

Technology Process of 27-Hydroxy-7-keto Cholesterol

There total 1 articles about 27-Hydroxy-7-keto Cholesterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

26-hydroxycholesterol (13095-61-9,26259-77-8) → 3β,27-dihydoxycholest-5-en-7-one (148988-28-7)

Guidance literature:

With tert.-butylhydroperoxide; dirhodium(II) tetrakis(caprolactam); In water; 1,2-dichloro-ethane; at 40 ℃; for 20h;

DOI:10.1021/ol7025284

upstream raw materials:

26-hydroxycholesterol