26-Hydroxycholesterol

Base Information

Chemical Name:26-Hydroxycholesterol
CAS No.:13095-61-9
Molecular Formula:C₂₇H₄₆O₂
Molecular Weight:402.661
Hs Code.:
DSSTox Substance ID:DTXSID101314679
Nikkaji Number:J533.768B
Wikidata:Q27102543
Pharos Ligand ID:MXU8YHLR1UM8
Metabolomics Workbench ID:34384
ChEMBL ID:CHEMBL3217768
Mol file:13095-61-9.mol

Synonyms:(25R,S)-26-hydroxycholesterol;26-hydroxycholesterol;cholest-5-ene-3 beta,26-diol;cholest-5-ene-3-beta,26-diol

Suppliers and Price of 26-Hydroxycholesterol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
（25R）-26-hydroxycholesterol ≥98%
10mg
$ 540.00

Total 14 raw suppliers

Chemical Property of 26-Hydroxycholesterol

Chemical Property:

Vapor Pressure:7.43E-13mmHg at 25°C
Melting Point:170-175 °C
Boiling Point:517.1°Cat760mmHg
PKA:15.03±0.70(Predicted)
Flash Point:215.6°C
PSA：40.46000
Density:1.03g/cm³
LogP:6.36110
XLogP3:7.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:402.349780706
Heavy Atom Count:29
Complexity:612

Purity/Quality:

99.5% ^*data from raw suppliers

（25R）-26-hydroxycholesterol ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)CO
Isomeric SMILES:C[C@H](CCCC(C)CO)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C
Uses 26-Hydroxycholesterol is a desmosterol metabolite that is found in the brain. 26-Hydroxycholesterol has been used as a biomarker for carbon cycling in the northwestern Mediterranean Sea.

Technology Process of 26-Hydroxycholesterol

There total 115 articles about 26-Hydroxycholesterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 79045-93-5
3β,26-dibezoyloxycholest-5-ene-16β-ol mesylate

: 13095-61-9,13095-71-1,56845-83-1,80695-35-8,96553-74-1,96553-75-2,20380-11-4,26259-77-8
(25R)-cholest-5-ene-3β,26-diol

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; Heating;
DOI:10.1016/S0040-4020(01)92435-4

Reference yield: 96.0%

: 43204-21-3
(20R,25R)-cholest-5-ene-3β,26-diol 3,26-diacetate

: 13095-61-9,13095-71-1,56845-83-1,80695-35-8,96553-74-1,96553-75-2,20380-11-4,26259-77-8
(25R)-cholest-5-ene-3β,26-diol

Guidance literature:: With potassium carbonate; In methanol; for 1h; Heating;
DOI:10.1021/jo00213a031

Reference yield: 90.0%

: 17367-15-6
(25ξ)-26-hydroxycholesteryl diacetate

: 13095-61-9,26259-77-8
26-hydroxycholesterol

Guidance literature:: With lipase from Candida cylindracea; octanol; In various solvent(s); at 37 ℃; for 144h;
DOI:10.1016/S0040-4039(00)96910-7