2,5-Dimethyltryptamine

Base Information

• Chemical Name: 2,5-Dimethyltryptamine
• CAS No.: 1079-44-3
• Molecular Formula: C12H16N2
• Molecular Weight: 188.27
• Hs Code.: 2933990090
• European Community (EC) Number: 877-967-8
• DSSTox Substance ID: DTXSID10292030
• Nikkaji Number: J46.793F
• Wikidata: Q63392360
• Mol file: 1079-44-3.mol

Synonyms:2,5-Dimethyltryptamine;1079-44-3;2-(2,5-Dimethyl-1H-indol-3-yl)-ethylamine;2-(2,5-Dimethyl-1H-indol-3-yl)ethanamine;2-(2,5-dimethyl-1H-indol-3-yl)ethan-1-amine;[2-(2,5-dimethyl-1H-indol-3-yl)ethyl]amine hydrochloride;2-(2,5-Dimethyl-1H-indol-3-yl)-ethylamine hydrochloride;Oprea1_178910;Oprea1_476154;SCHEMBL7886752;DTXSID10292030;STK014860;AKOS000275797;NCGC00330775-01;2-(2,5-Dimethyl-1H-indol-3-yl)ethylamine;BB 0218152;FT-0677835;3-(2-AMINOETHYL)-2,5-DIMETHYLINDOLE;2-(2,5-Dimethyl-1H-indol-3-yl)ethanamine #;EN300-110466;AB01325349-02;Q63392360;F2169-0217;Z1198153447

Chemical Property of 2,5-Dimethyltryptamine

Chemical Property:

• Vapor Pressure: 1.44E-05mmHg at 25°C
• Boiling Point: 366.7°C at 760 mmHg
• PKA: 17.95±0.30(Predicted)
• Flash Point: 203.2°C
• PSA: 41.81000
• Density: 1.101g/cm³
• LogP: 2.98620
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 188.131348519
• Heavy Atom Count: 14
• Complexity: 193

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(2,5-Dimethyl-1H-indol-3-yl)-ethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(C=C1)NC(=C2CCN)C
• Uses: [2-(2,5-Dimethyl-1H-indol-3-yl)ethyl]amine is used as a reactant in the total synthesis of (+)-minfiensine and related compounds via asymmetric cascade cyclization.

Technology Process of 2,5-Dimethyltryptamine

There total 2 articles about 2,5-Dimethyltryptamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloro-2-pentanone (5891-21-4) + N-4-methylphenylhydrazine (539-44-6) → 2-(2,5-dimethyl-1H-indol-3-yl)ethan-1-amine (1079-44-3)

Guidance literature:

In ethanol; Reflux;

DOI:10.1039/c7cc02419c

Reference yield:

→ 2-(2,5-dimethyl-1H-indol-3-yl)ethan-1-amine (1079-44-3)

Guidance literature:

4-Methyl-phenylhydrazin, γ-Chlor-propyl-methylketon, sd. wss. CH3OH;

DOI:10.1007/BF00481041

Reference yield:

4-chloro-6-(2,3-dimethylphenyl)pyrimidin-2-amine (1612184-09-4) + 2-(2,5-dimethyl-1H-indol-3-yl)ethan-1-amine (1079-44-3) → 4-N-[2-(2,5-dimethyl-1H-indol-3-yl)ethyl]-6-(2,3-dimethylphenyl)pyrimidine-2,4-diamine (1612182-00-9)

Guidance literature:

In neat (no solvent); at 150 ℃; for 1h;

upstream raw materials:

5-chloro-2-pentanone

N-4-methylphenylhydrazine

Downstream raw materials:

4-N-[2-(2,5-dimethyl-1H-indol-3-yl)ethyl]-6-(2,3-dimethylphenyl)pyrimidine-2,4-diamine

Refernces

• 1、 Grandberg,I.I.,Zuyanova,T.I.. "-". . . Retrieved 1968.