3-Benzyl-1-methylpiperidine-2,6-dione

Base Information

Chemical Name:3-Benzyl-1-methylpiperidine-2,6-dione
CAS No.:124482-68-4
Molecular Formula:C13H15NO2
Molecular Weight:217.2637
Hs Code.:2925190090
ChEMBL ID:CHEMBL173390
DSSTox Substance ID:DTXSID20561325
Nikkaji Number:J274.882G
Mol file:124482-68-4.mol

Synonyms:3-Benzyl-1-methylpiperidine-2,6-dione;124482-68-4;1-METHYL-3-(PHENYLMETHYL)-2,6-PIPERIDINEDIONE;SCHEMBL717587;CHEMBL173390;DTXSID20561325;CS-B1098;ZEA48268;MFCD25542393;SY263330;A890503

Suppliers and Price of 3-Benzyl-1-methylpiperidine-2,6-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Benzyl-1-methylpiperidine-2,6-dione 95+%
250mg
$ 436.00

Crysdot
3-Benzyl-1-methylpiperidine-2,6-dione 95+%
1g
$ 1089.00

Chemenu
3-Benzyl-1-methylpiperidine-2,6-dione 95%
1g
$ 1018.00

Alichem
3-Benzyl-1-methylpiperidine-2,6-dione
1g
$ 1224.30

Alichem
3-Benzyl-1-methylpiperidine-2,6-dione
250mg
$ 466.62

AK Scientific
3-Benzyl-1-methylpiperidine-2,6-dione
1g
$ 1268.00

Total 9 raw suppliers

Chemical Property of 3-Benzyl-1-methylpiperidine-2,6-dione

Chemical Property:

Melting Point:61-63 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
Boiling Point:369.6±11.0 °C(Predicted)
PKA:-1.42±0.40(Predicted)
PSA：37.38000
Density:1.150±0.06 g/cm3(Predicted)
LogP:1.56200
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:217.110278721
Heavy Atom Count:16
Complexity:282

Purity/Quality:

97% ^*data from raw suppliers

3-Benzyl-1-methylpiperidine-2,6-dione 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=O)CCC(C1=O)CC2=CC=CC=C2

Technology Process of 3-Benzyl-1-methylpiperidine-2,6-dione

There total 2 articles about 3-Benzyl-1-methylpiperidine-2,6-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 97938-45-9
3-benzylpiperidine-2,6-dione

: 74-88-4
methyl iodide

: 124482-68-4
3-Benzyl-1-methyl-piperidine-2,6-dione

Guidance literature:: With potassium hydroxide; In acetone; Heating;
DOI:10.1021/jm00165a007

Reference yield:

: 1121-89-7
piperidine-2,6-dione

: 124482-68-4
3-Benzyl-1-methyl-piperidine-2,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Na/liquid NH₃, Fe(NO₃)3*9H₂O / 1.) 30 min, 2.) ether, 1 h

2: 66 percent / KOH / acetone / Heating

With potassium hydroxide; ammonia; sodium; In acetone;
DOI:10.1021/jm00165a007