GpGp

Base Information

• Chemical Name: GpGp
• CAS No.: 17332-09-1
• Molecular Formula: C20H26 N10 O15 P2
• Molecular Weight: 708.43
• Mol file: 17332-09-1.mol

Synonyms:3'-Guanylicacid, bimol. 3',5'''-ester (6CI); Guanosine, 3'-O-phosphorylguanylyl-(5'®3')- (7CI,8CI); Guanylyl-(3'®5')-guanylic acid

Chemical Property of GpGp

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 1354.8°C at 760 mmHg
• Flash Point: 773.2°C
• PSA: 413.45000
• Density: 2.69g/cm³
• LogP: -3.67460

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of GpGp

There total 5 articles about GpGp which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis-(3′,5′)-cyclic dimeric guanosine monophosphate (61093-23-0) → pGpG (17332-09-1)

Guidance literature:

With water; rocR; In aq. buffer; at 37 ℃; for 0.05h; Kinetics; Enzymatic reaction;

Reference yield:

Guanosine 5'-triphosphate (86-01-1,72490-81-4) → pGpG (17332-09-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Vibrio cholerae dinucleotide cyclase / aq. buffer / 0.67 h / 37 °C / pH 7.5 / Enzymatic reaction

2: rocR; water / aq. buffer / 0.05 h / 37 °C / Enzymatic reaction

With water; rocR; Vibrio cholerae dinucleotide cyclase; In aq. buffer;

Reference yield:

guanosine 2',3'-cyclic monophosphate (634-02-6) → pGpG (17332-09-1)

Guidance literature:

With guanylribonuclease;

DOI:10.1016/0006-3002(58)90032-5

upstream raw materials:

guanosine 2',3'-cyclic monophosphate

Guanosine 5'-triphosphate

bis-(3′,5′)-cyclic dimeric guanosine monophosphate

Refernces

• 1、 -. "CYCLIC DINUCLEOTIDE COMPOUNDS AS STING AGONISTS". . . Retrieved 2021/04/10.