tert-butyl N-[2-[(5-fluoro-2-nitro-benzoyl)amino]ethyl]carbamate

Base Information

• Chemical Name: tert-butyl N-[2-[(5-fluoro-2-nitro-benzoyl)amino]ethyl]carbamate
• CAS No.: 947258-24-4
• Molecular Formula: C14H18FN3O5
• Molecular Weight: 327.312
• Mol file: 947258-24-4.mol

Synonyms:tert-Butyl 2-(5-fluoro-2-nitrobenzamido)ethylcarbamate

Chemical Property of tert-butyl N-[2-[(5-fluoro-2-nitro-benzoyl)amino]ethyl]carbamate

Chemical Property:

• PSA: 113.25000
• LogP: 3.29340

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl N-[2-[(5-fluoro-2-nitro-benzoyl)amino]ethyl]carbamate

There total 1 articles about tert-butyl N-[2-[(5-fluoro-2-nitro-benzoyl)amino]ethyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

N-BOC-1,2-diaminoethane (57260-73-8) → [2-(5-fluoro-2-nitro-benzoylamino)-ethyl]-carbamic acid tert-butyl ester (947258-24-4)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In acetonitrile; for 18h;

Reference yield: 61.0%

[2-(5-fluoro-2-nitro-benzoylamino)-ethyl]-carbamic acid tert-butyl ester (947258-24-4) + sodium thiomethoxide (5188-07-8) → C15H21N3O5S (947258-25-5)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 2h;

upstream raw materials:

N-BOC-1,2-diaminoethane

Downstream raw materials:

C₁₅H₂₁N₃O₅S

Refernces