Basmisanil

Base Information

Chemical Name:Basmisanil
CAS No.:1159600-41-5
Molecular Formula:C21H20FN3O5S
Molecular Weight:445.471
Hs Code.:
Mol file:1159600-41-5.mol

Synonyms:Basmisanil;(1,1-Dioxo-4-thiomorpholinyl)[6-[[3-(4-fluorophenyl)-5-methylisoxazol-4-yl]methoxy]pyridin-3-yl]methanone;RG 1662;RG-1662;RO5186582;Ladarixin

Suppliers and Price of Basmisanil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Basmisanil
1mg
$ 45.00

TRC
Basmisanil
5mg
$ 110.00

DC Chemicals
Basmisanil(RG1662) >98%
1 g
$ 2400.00

DC Chemicals
Basmisanil(RG1662) >98%
250 mg
$ 1200.00

Crysdot
Basmisanil 98+%
10mg
$ 283.00

Crysdot
Basmisanil 98+%
50mg
$ 974.00

Crysdot
Basmisanil 98+%
25mg
$ 567.00

ChemScene
Basmisanil 99.49%
100mg
$ 435.00

ChemScene
Basmisanil 99.49%
10mg
$ 85.00

ChemScene
Basmisanil 99.49%
50mg
$ 255.00

Total 18 raw suppliers

Chemical Property of Basmisanil

Chemical Property:

Boiling Point:726.6±60.0 °C(Predicted)
PKA:2.07±0.22(Predicted)
PSA：110.98000
Density:1.388±0.06 g/cm3(Predicted)
LogP:3.65240
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

Basmisanil ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Basmisanil is a highly selective GABAAα5 negative allosteric modulator.

Technology Process of Basmisanil

There total 11 articles about Basmisanil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.7%

: 1159600-32-4
6-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid

: 59801-62-6
1,1-dioxothiomorpholine hydrochloride

: 1159600-41-5
(1,1-dioxo-1λ⁶-thiomorpholin-4-yl)-{6-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-pyridin-3-yl}-methanone

Guidance literature:: With dmap; triethylamine; 1,1'-carbonyldiimidazole; In tetrahydrofuran; for 50h; Temperature; Concentration; Reagent/catalyst; Time; Solvent; Reflux;

Reference yield: 86.0%

: 39093-93-1
thiomorpholine 1,1-dioxide

: 1159600-32-4
6-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid

: 1159600-41-5
(1,1-dioxo-1λ⁶-thiomorpholin-4-yl)-{6-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-pyridin-3-yl}-methanone

Guidance literature:: 6-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 1h;

thiomorpholine 1,1-dioxide; With dmap; triethylamine; In tetrahydrofuran; Reagent/catalyst; Solvent; Time; Temperature; Reflux;