GW 501516 Methyl Ester

Base Information

Chemical Name:GW 501516 Methyl Ester
CAS No.:317318-69-7
Molecular Formula:C22H20F3NO3S2
Molecular Weight:467.533
Hs Code.:
DSSTox Substance ID:DTXSID20460389
Wikidata:Q82284424
Mol file:317318-69-7.mol

Synonyms:GW 501516 Methyl Ester;317318-69-7;methyl 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetate;SCHEMBL6239544;DTXSID20460389;QODOIZHAPCCMJN-UHFFFAOYSA-N;AKOS030254736;AS-0549;Methyl-methyl-trifluoromethylphenyl-thiazolyl-methylsulfanyl-phenoxy-acetic Acid Methyl Ester;FT-0669088;J-018518;methyl 2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetate

Suppliers and Price of GW 501516 Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
GW501516MethylEster
10mg
$ 250.00

Medical Isotopes, Inc.
GW501516MethylEster
50 mg
$ 2120.00

Medical Isotopes, Inc.
GW501516MethylEster
5 mg
$ 640.00

Total 17 raw suppliers

Chemical Property of GW 501516 Methyl Ester

Chemical Property:

Melting Point:93-95?C
Boiling Point:553.8±60.0 °C(Predicted)
PKA:1.92±0.10(Predicted)
PSA：101.96000
Density:1.36±0.1 g/cm3(Predicted)
LogP:6.28980
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly)
XLogP3:6.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:8
Exact Mass:467.08367033
Heavy Atom Count:31
Complexity:587

Purity/Quality:

99% ,98%,Electron Grade , ^*data from raw suppliers

GW501516MethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)SCC2=C(N=C(S2)C3=CC=C(C=C3)C(F)(F)F)C)OCC(=O)OC
Uses Precursor to GW 501516.

Technology Process of GW 501516 Methyl Ester

There total 19 articles about GW 501516 Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 317318-69-7
methyl [2-methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]thiazol-5-yl]methyl]sulfanyl]peroxy]acetate

Guidance literature:

Reference yield:

: 175277-03-9
4-methyl-2-[4-(trifluoromethyl)phenyl]thiazole-5-carboxylic acid ethyl ester

: 317318-69-7
methyl [2-methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]thiazol-5-yl]methyl]sulfanyl]peroxy]acetate

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / LiAlH₄ / tetrahydrofuran / 20 °C

2: 90 percent / MeSO₂Cl; Et₃N / CH₂Cl₂ / 0 °C

3: Cs₂CO₃ / acetonitrile / 16 h / 20 °C

With lithium aluminium tetrahydride; caesium carbonate; methanesulfonyl chloride; triethylamine; In tetrahydrofuran; dichloromethane; acetonitrile; 3: Williamson reaction;
DOI:10.1016/S0960-894X(03)00207-5