alpha-Oxo-4-Pyridinepropanoic acid ethyl ester

Base Information

• Chemical Name: alpha-Oxo-4-Pyridinepropanoic acid ethyl ester
• CAS No.: 103204-67-7
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193.202
• Mol file: 103204-67-7.mol

Synonyms:alpha-Oxo-4-Pyridinepropanoic acid ethyl ester;α-Oxo-4-pyridinepropanoic acid ethyl ester;ethyl 2-oxo-3-(pyridin-4-yl)propanoate

Chemical Property of alpha-Oxo-4-Pyridinepropanoic acid ethyl ester

Chemical Property:

• Boiling Point: 324.2±25.0 °C(Predicted)
• PKA: 4.98±0.10(Predicted)
• PSA: 66.24000
• Density: 1.166±0.06 g/cm3(Predicted)
• LogP: -0.11220

Purity/Quality:

98%min ^*data from raw suppliers

ethyl2-oxo-3-(pyridin-4-yl)propanoate 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of alpha-Oxo-4-Pyridinepropanoic acid ethyl ester

There total 2 articles about alpha-Oxo-4-Pyridinepropanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

picoline (108-89-4) + oxalic acid diethyl ester (95-92-1) → -brenztraubensaeure-ethylester (103204-67-7)

Guidance literature:

With potassium tert-butylate; In diethyl ether; Ambient temperature;

DOI:10.1080/00397919208019078

Reference yield:

→ -brenztraubensaeure-ethylester (103204-67-7)

Guidance literature:

4-Picolyl-quecksilber, Oxalsaeure-ethylester (-70grad);

upstream raw materials:

picoline

oxalic acid diethyl ester