Technology Process of 5-(benzhydryloxy)-4,5-dioxopentanoic acid
There total 1 articles about 5-(benzhydryloxy)-4,5-dioxopentanoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
formaldehyd;
With
diisopropylamine;
In
N,N-dimethyl acetamide;
at 60 ℃;
for 0.75h;
1-diphenylmethyl 2-oxoglutarate;
With
trifluoroacetic acid;
In
N,N-dimethyl acetamide;
at 0 - 60 ℃;
for 0.75h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: diisopropylamine / N,N-dimethyl acetamide / 0.75 h / 60 °C
1.2: 0.75 h / 0 - 60 °C
2.1: quinindine / 4.75 h / 20 °C
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.33 h / 20 °C
4.1: phosphorus pentachloride; pyridine / dichloromethane; ethanol / 2.5 h / -78 - 0 °C
5.1: O-phenyl phosphorodichloridate; 4-methyl-morpholine / ethyl acetate / 1 h / -30 °C
With
4-methyl-morpholine; pyridine; phosphorus pentachloride; quinindine; O-phenyl phosphorodichloridate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; diisopropylamine;
In
ethanol; dichloromethane; N,N-dimethyl acetamide; ethyl acetate;
