Methyl 2-(3-broMophenyl)-2-Methylpropanoate

Base Information

• Chemical Name: Methyl 2-(3-broMophenyl)-2-Methylpropanoate
• CAS No.: 251458-15-8
• Molecular Formula: C11H13BrO2
• Molecular Weight: 257.127
• Hs Code.: 2916399090
• Mol file: 251458-15-8.mol

Synonyms:Methyl 2-(3-broMophenyl)-2-Methylpropanoate;2-(3-Bromo-phenyl)-2-methyl-propionic acid methyl ester;Benzeneacetic acid, 3-bromo-α,α-dimethyl-, methyl ester

Chemical Property of Methyl 2-(3-broMophenyl)-2-Methylpropanoate

Chemical Property:

• PSA: 26.30000
• LogP: 2.89970
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-(3-bromophenyl)-2-methylpropanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 2-(3-broMophenyl)-2-Methylpropanoate

There total 4 articles about Methyl 2-(3-broMophenyl)-2-Methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

methyl 2-(3-bromophenyl)acetatee (150529-73-0) + methyl iodide (74-88-4) → methyl 2-(3-bromophenyl)-2-methylpropanoate (251458-15-8)

Guidance literature:

methyl 2-(3-bromophenyl)acetatee; With sodium hydride; In tetrahydrofuran; mineral oil; at 50 ℃; for 2h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; mineral oil; at 20 - 40 ℃;

Reference yield: 36.0%

2-(3-bromo-phenyl)-2-methyl-propionitrile (90433-20-8) → methyl 2-(3-bromophenyl)-2-methylpropanoate (251458-15-8)

Guidance literature:

With acetic acid; In sulfuric acid; water;

Reference yield:

methyl iodide (74-88-4) → methyl 2-(3-bromophenyl)-2-methylpropanoate (251458-15-8)

Guidance literature:

methyl 2-(3-bromophenyl)acetatee; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.333333h;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

upstream raw materials:

methyl 2-(3-bromophenyl)acetatee

methyl iodide

2-(3-bromo-phenyl)-2-methyl-propionitrile

Downstream raw materials:

2-(3-bromophenyl)-2-methylpropanoic acid

2-methyl-2-[3-(2-pyridyl)phenyl]propionic acid methyl ester

2,2-dimethyl-2-(3-bromophenyl)ethanol

methyl 2-methyl-2-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate