tert-butyl 4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate
CAS No.:883738-19-0
Molecular Formula:C22H35BN2O4
Molecular Weight:402.342
Hs Code.:2933998090
Mol file:883738-19-0.mol

Synonyms:tert-butyl 4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate;3-{[4-(tert-Butoxycarbonyl)piperazin-1-yl]methyl}benzeneboronicacid,pinacolester

Suppliers and Price of tert-butyl 4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(4-Boc-1-piperazinylmethyl)benzeneboronicacidpinacolester
250mg
$ 55.00

TRC
3-(4-Boc-1-piperazinylmethyl)benzeneboronicacidpinacolester
1g
$ 75.00

SynQuest Laboratories
3-{[4-(tert-Butoxycarbonyl)piperazin-1-yl]methyl}benzeneboronic acid, pinacol ester 98%
1 g
$ 90.00

SynQuest Laboratories
3-{[4-(tert-Butoxycarbonyl)piperazin-1-yl]methyl}benzeneboronic acid, pinacol ester 98%
5 g
$ 274.00

Matrix Scientific
3-((4-Boc-piperazine)methyl) phenylboronic-acid pinacol ester >95%
5g
$ 332.00

Matrix Scientific
3-((4-Boc-piperazine)methyl) phenylboronic-acid pinacol ester >95%
500mg
$ 62.00

Matrix Scientific
3-((4-Boc-piperazine)methyl) phenylboronic-acid pinacol ester >95%
1g
$ 83.00

Crysdot
tert-Butyl4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate 95+%
25g
$ 527.00

Chemenu
tert-Butyl4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate 98%
5g
$ 124.00

Chemenu
tert-Butyl4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate 98%
25g
$ 485.00

Total 5 raw suppliers

Chemical Property of tert-butyl 4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate

Chemical Property:

PSA：51.24000
LogP:2.91430

Purity/Quality:

97% ^*data from raw suppliers

3-(4-Boc-1-piperazinylmethyl)benzeneboronicacidpinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate

There total 3 articles about tert-butyl 4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 380151-86-0
3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarboxaldehyde

: 883738-19-0
1,1-dimethylethyl 4-{[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}-1-piperazinecarboxylate

Guidance literature:: 1-t-Butoxycarbonylpiperazine; 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarboxaldehyde; With acetic acid; In DCM; at 20 ℃;

With sodium tris(acetoxy)borohydride; In dichloromethane; at 10 - 15 ℃; for 0.166667h;

Reference yield: 90.0%

: 865314-27-8
tert-butyl 4-(3-bromobenzyl)piperazine-1-carboxylate

: 73183-34-3
bis(pinacol)diborane

: 883738-19-0
1,1-dimethylethyl 4-{[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}-1-piperazinecarboxylate

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In N,N-dimethyl-formamide; at 80 ℃; for 4h;