ERYTHRO-2-ANILINO-1 2-DIPHENYL-

Base Information

• Chemical Name: ERYTHRO-2-ANILINO-1 2-DIPHENYL-
• CAS No.: 210571-76-9
• Molecular Formula: C₂₀H₁₉NO
• Molecular Weight: 289.377
• Mol file: 210571-76-9.mol

Synonyms:ERYTHRO-2-ANILINO-1 2-DIPHENYL-

Chemical Property of ERYTHRO-2-ANILINO-1 2-DIPHENYL-

Chemical Property:

• Vapor Pressure: 5.67E-09mmHg at 25°C
• Melting Point: 122-127 °C(lit.)
• Boiling Point: 452.4°C at 760 mmHg
• Flash Point: 128.8°C
• Density: 1.177g/cm³

Purity/Quality:

97% ^*data from raw suppliers

ERYTHRO-2-ANILINO-1,2-DIPHENYLETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

Useful:

Technology Process of ERYTHRO-2-ANILINO-1 2-DIPHENYL-

There total 74 articles about ERYTHRO-2-ANILINO-1 2-DIPHENYL- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

aniline (62-53-3) + trans-Stilbene oxide (1439-07-2) → (1S,2R)-1,2-diphenyl-2-(phenylamino)ethanol (729609-98-7,210571-76-9) + (R,R)-trans-stilbene epoxide (1439-07-2)

Guidance literature:

With C₆₈H₉₂Cr₂N₈O₄⁽²⁺⁾*2Cl^(1-); In methanol; dichloromethane; at 20 ℃; for 18h; optical yield given as %ee; enantioselective reaction;

DOI:10.1016/j.tet.2011.08.077

Reference yield: 99.0%

aniline (62-53-3) + cis-1,2-diphenyloxirane (1689-71-0) → (1S,2S)-1,2-diphenyl-2-(phenylamino)ethanol (210571-76-9)

Guidance literature:

With indium(III) triflate; C₂₈H₄₈N₄O₄; In tetrahydrofuran; at 0 ℃; for 69h; optical yield given as %ee; enantioselective reaction; Molecular sieve; Inert atmosphere;

DOI:10.1002/adsc.200700474

Reference yield: 97.0%

aniline (62-53-3) + cis-1,2-diphenyloxirane (1689-71-0) → (1R,2R)-1,2-diphenyl-2-(phenylamino)ethanol (210571-76-9)

Guidance literature:

With 2C₁₂H₂₅O₃S^(1-)*Zn⁽²⁺⁾; (meso)-1,1'-([2,2'-bipyridine]-6,6'-diyl)bis(2,2-dimethylpropan-1-ol); In water; at 20 ℃; for 22h; enantioselective reaction;

DOI:10.1016/j.tet.2009.11.018

upstream raw materials:

1,2-diphenyl-2-(phenylamino)ethanone

chloro-trimethyl-silane

benzylidene phenylamine

benzaldehyde

Downstream raw materials:

3,4,5-triphenyl-oxazolidin-2-one

benzophenone

cis-3,4,5-triphenyl-1,3-oxazolidin-2-one

4,5-cis-2-(p-methoxyphenyl)-3,4,5-triphenyloxazolidine