4-(Thiophen-2-yl)benzene-1,2-diamine

Base Information

Chemical Name:4-(Thiophen-2-yl)benzene-1,2-diamine
CAS No.:471239-63-1
Molecular Formula:C₁₀H₁₀N₂S
Molecular Weight:190.269
Hs Code.:
UNII:E9EDG3RM2C
ChEMBL ID:CHEMBL495702
Mol file:471239-63-1.mol

Synonyms:4-(thiophen-2-yl)benzene-1,2-diamine;471239-63-1;4-(2-thienyl)-1,2-Benzenediamine;E9EDG3RM2C;CHEMBL495702;SCHEMBL2873589;XWTMGMKBRLLEFX-UHFFFAOYSA-N;1,2-Diamino-4-(2-thienyl)benzene;4-thiophen-2-ylbenzene-1,2-diamine;AKOS033921192;1,2-Benzenediamine, 4-(2-thienyl)-;PD181666;FT-0738633;EN300-266833;Z1262633780

Suppliers and Price of 4-(Thiophen-2-yl)benzene-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-(Thiophen-2-yl)benzene-1,2-diamine

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:190.05646950
Heavy Atom Count:13
Complexity:174

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CSC(=C1)C2=CC(=C(C=C2)N)N

Technology Process of 4-(Thiophen-2-yl)benzene-1,2-diamine

There total 5 articles about 4-(Thiophen-2-yl)benzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 405170-93-6
2-nitro-4-thiophen-2-yl-phenylamine

: 471239-63-1
4-(thiophen-2-yl)benzene-1,2-diamine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; under 760.051 Torr;

Reference yield:

: 5228-61-5
5-bromo-2-nitroaniline

: 471239-63-1
4-(thiophen-2-yl)benzene-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / tetrahydrofuran; water / 12 h / 70 °C

2: iron(III) chloride; hydrazine hydrate / methanol

With iron(III) chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; hydrazine hydrate; In tetrahydrofuran; methanol; water; 1: |Suzuki Coupling;
DOI:10.1134/S1070363217110202