3-Diethoxyphosphoryloxy-7,11,15-trimethyl-hexadecatetra-2,6,10,14-enoic Acid, Ethyl Ester, (Mixture of Isomers)

Base Information

Chemical Name:3-Diethoxyphosphoryloxy-7,11,15-trimethyl-hexadecatetra-2,6,10,14-enoic Acid, Ethyl Ester, (Mixture of Isomers)
CAS No.:887354-51-0
Molecular Formula:C₂₅H₄₃O₆P
Molecular Weight:470.587
Hs Code.:
Mol file:887354-51-0.mol

Synonyms:3-Diethoxyphosphoryloxy-7,11,15-trimethyl-hexadecatetra-2,6,10,14-enoic Acid, Ethyl Ester, (Mixture of Isomers);3-[(Diethoxyphosphinyl)oxy]-7,11,15-triMethyl-2,6,10,14-hexadecatetraenoic Acid Ethyl Ester

Suppliers and Price of 3-Diethoxyphosphoryloxy-7,11,15-trimethyl-hexadecatetra-2,6,10,14-enoic Acid, Ethyl Ester, (Mixture of Isomers)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Diethoxyphosphoryloxy-7,11,15-trimethyl-hexadecatetra-2,6,10,14-enoicAcid,EthylEster,(MixtureofIsomers)
2.5g
$ 970.00

American Custom Chemicals Corporation
(2E,6E,10E)-3-DIETHOXYPHOSPHORYLOXY-7,11,15-TRIMETHYL-HEXADECATETRA-2,6,10,14-ENOIC ACID ETHYL ESTER 95.00%
5MG
$ 499.30

Total 2 raw suppliers

Chemical Property of 3-Diethoxyphosphoryloxy-7,11,15-trimethyl-hexadecatetra-2,6,10,14-enoic Acid, Ethyl Ester, (Mixture of Isomers)

Chemical Property:

PSA：80.87000
LogP:7.83050
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

3-Diethoxyphosphoryloxy-7,11,15-trimethyl-hexadecatetra-2,6,10,14-enoicAcid,EthylEster,(MixtureofIsomers) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses A intermediate in the lipidation of proteins, which plays a great importance for a variety of biological processes such as cell signalling.

Technology Process of 3-Diethoxyphosphoryloxy-7,11,15-trimethyl-hexadecatetra-2,6,10,14-enoic Acid, Ethyl Ester, (Mixture of Isomers)

There total 6 articles about 3-Diethoxyphosphoryloxy-7,11,15-trimethyl-hexadecatetra-2,6,10,14-enoic Acid, Ethyl Ester, (Mixture of Isomers) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 814-49-3
diethyl chlorophosphate

: 141538-75-2
(6E,10E)-ethyl 7,11,15-trimethyl-3-oxohexadeca-6,10,14-trienoate

: 887354-51-0
C₂₅H₄₃O₆P

Guidance literature:: With dmap; triethylamine; In 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; at -30 - 20 ℃; for 3h; stereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2011.09.114

Reference yield:

: 814-49-3
diethyl chlorophosphate

: 141538-75-2
(6E,10E)-ethyl 7,11,15-trimethyl-3-oxohexadeca-6,10,14-trienoate

: 887354-51-0
(2Z,6E,10E)-ethyl 7,11,15-trimethyl-3-diethylphosphoryloxy-6,10,14-trienoate

Guidance literature:: (6E,10E)-ethyl 7,11,15-trimethyl-3-oxohexadeca-6,10,14-trienoate; With sodium hydride; In diethyl ether; at 0 - 21 ℃; for 0.75h; Schlenk technique;

diethyl chlorophosphate; In diethyl ether; at 0 ℃; for 0.25h; Schlenk technique;
DOI:10.1016/j.chembiol.2014.07.022

Reference yield:

: 24163-93-7,24163-94-8,56881-57-3,6874-67-5,28290-41-7
farnesyl bromide

: 887354-51-0
(2Z,6E,10E)-ethyl 7,11,15-trimethyl-3-diethylphosphoryloxy-6,10,14-trienoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 0.08 h / 0 °C / Schlenk technique

1.2: 0.5 h / 0 °C / Schlenk technique

1.3: 0.25 h / 0 °C / Schlenk technique

2.1: sodium hydride / diethyl ether / 0.75 h / 0 - 21 °C / Schlenk technique

2.2: 0.25 h / 0 °C / Schlenk technique

With sodium hydride; In tetrahydrofuran; diethyl ether;
DOI:10.1016/j.chembiol.2014.07.022