2-Thiophenecarboxylic acid, 5-[3-(trifluoromethyl)phenyl]-, methyl ester

Base Information

Chemical Name:2-Thiophenecarboxylic acid, 5-[3-(trifluoromethyl)phenyl]-, methyl ester
CAS No.:1024448-98-3
Molecular Formula:C₁₃H₉F₃O₂S
Molecular Weight:286.274
Hs Code.:
Mol file:1024448-98-3.mol

Synonyms:2-Thiophenecarboxylic acid, 5-[3-(trifluoromethyl)phenyl]-, methyl ester;5-[3-(trifluoromethyl)phenyl]-2-Thiophenecarboxylic acid methyl

Suppliers and Price of 2-Thiophenecarboxylic acid, 5-[3-(trifluoromethyl)phenyl]-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 2-Thiophenecarboxylic acid, 5-[3-(trifluoromethyl)phenyl]-, methyl ester

Chemical Property:

PSA：54.54000
LogP:4.22050

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Thiophenecarboxylic acid, 5-[3-(trifluoromethyl)phenyl]-, methyl ester

There total 3 articles about 2-Thiophenecarboxylic acid, 5-[3-(trifluoromethyl)phenyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7311-63-9
5-bromothiophene-2-carboxylic acid

: 1024448-98-3
5-(3-trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: aq. Na₂CO₃; Pd(PPh₃)4; NMP / Heating

With 1-methyl-pyrrolidin-2-one; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; 1: Suzuki coupling;
DOI:10.1016/j.bmcl.2004.07.028

Reference yield:

: 1423-26-3
(meta-(trifluoromethyl)phenyl)boronic acid

: 1024448-98-3
5-(3-trifluoromethyl-phenyl)-thiophene-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: aq. Na₂CO₃; Pd(PPh₃)4; NMP / Heating

With 1-methyl-pyrrolidin-2-one; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; 1: Suzuki coupling;
DOI:10.1016/j.bmcl.2004.07.028