tert-Butyl 2-Boc-aMinobenzylcarbaMate

Base Information

• Chemical Name: tert-Butyl 2-Boc-aMinobenzylcarbaMate
• CAS No.: 263403-72-1
• Molecular Formula: C17H26N2O4
• Molecular Weight: 322.39934
• Mol file: 263403-72-1.mol

Synonyms:tert-Butyl 2-Boc-aMinobenzylcarbaMate

Chemical Property of tert-Butyl 2-Boc-aMinobenzylcarbaMate

Chemical Property:

• PSA: 83.64000
• LogP: 4.27630
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl2-Boc-aminobenzylcarbamate >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tert-Butyl 2-Boc-aMinobenzylcarbaMate

There total 2 articles about tert-Butyl 2-Boc-aMinobenzylcarbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

di-tert-butyl dicarbonate (24424-99-5) + 2-amino-1-benzylamine (4403-69-4) → o-aminobenzylamine tert-butyl dicarbamate (263403-72-1)

Guidance literature:

In acetonitrile; Inert atmosphere;

DOI:10.1016/j.tet.2017.06.039

Reference yield: 30.0%

phenylacetic acid (103-82-2) + di-tert-butyl dicarbonate (24424-99-5) → N-tert-butoxycarbonylbenzylamine (42116-44-9) + o-aminobenzylamine tert-butyl dicarbamate (263403-72-1)

Guidance literature:

phenylacetic acid; With sodium azide; sulfuric acid; In chloroform; for 3h; Heating;

di-tert-butyl dicarbonate; With triethylamine; In methanol; at 20 ℃; Further stages.;

upstream raw materials:

phenylacetic acid

di-tert-butyl dicarbonate

2-amino-1-benzylamine