Raloxifene N-Oxide

Base Information

Chemical Name:Raloxifene N-Oxide
CAS No.:195454-31-0
Molecular Formula:C₂₈H₂₇NO₅S
Molecular Weight:489.592
Hs Code.:2934990002
UNII:X1BRV5W297
DSSTox Substance ID:DTXSID50173218
Wikidata:Q27293303
Mol file:195454-31-0.mol

Synonyms:Raloxifene N-Oxide;195454-31-0;UNII-X1BRV5W297;X1BRV5W297;Raloxifene hydrochloride impurity C [EP];(6-Hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone N-oxide;[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-[2-(1-oxidopiperidin-1-ium-1-yl)ethoxy]phenyl]methanone;Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-oxido-1-piperidinyl)ethoxy)phenyl)-;SCHEMBL3667715;DTXSID50173218;AKOS040744358;[6-Hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl][4-[2-(piperidin-1-yl)ethoxy]phenyl]methanone N-Oxide (Raloxifene N-Oxide);HY-135586;CS-0113555;J-012662;Q27293303;RALOXIFENE HYDROCHLORIDE IMPURITY C [EP IMPURITY]

Suppliers and Price of Raloxifene N-Oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Raloxifene N-oxide
500mg
$ 2683.00

TRC
RaloxifeneN-Oxide
5mg
$ 105.00

TRC
RaloxifeneN-Oxide
100mg
$ 1155.00

Sigma-Aldrich
Raloxifene Related Compound C
20mg
$ 1160.00

Sigma-Aldrich
Raloxifene Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material
40mg
$ 602.00

Biosynth Carbosynth
[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-oxido-1-piperidinyl)ethoxy]phenyl]methanone
2 mg
$ 46.00

American Custom Chemicals Corporation
RALOXIFENE IMPURITY C 95.00%
5MG
$ 496.99

Total 10 raw suppliers

Chemical Property of Raloxifene N-Oxide

Chemical Property:

PSA：124.43000
LogP:6.04660
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:5.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:489.16099414
Heavy Atom Count:35
Complexity:700

Purity/Quality:

99%, ^*data from raw suppliers

Raloxifene N-oxide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC[N+](CC1)(CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O)[O-]
Uses Raloxifene degradation material. Raloxifene N-Oxide (Raloxifene EP Impurity C) is a Raloxifene degradation material.

Technology Process of Raloxifene N-Oxide

There total 3 articles about Raloxifene N-Oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 82640-04-8
raloxifene hydrochloride

: 195454-31-0
raloxifene N-oxide

Guidance literature:: raloxifene hydrochloride; With sodium hydroxide; In methanol; water;

With dihydrogen peroxide; In methanol; water; at 20 ℃; chemoselective reaction;
DOI:10.1016/j.xphs.2018.10.059