N7-(4-Methoxyphenyl)-N2-phenylthiazolo[5,4-d]pyrimidine-2,7-diamine

Base Information

Chemical Name:N7-(4-Methoxyphenyl)-N2-phenylthiazolo[5,4-d]pyrimidine-2,7-diamine
CAS No.:871266-93-2
Molecular Formula:C₁₈H₁₅N₅OS
Molecular Weight:349.416
Hs Code.:
DSSTox Substance ID:DTXSID60470326
Wikidata:Q82298396
Mol file:871266-93-2.mol

Synonyms:N7-(4-Methoxyphenyl)-N2-phenylthiazolo[5,4-d]pyrimidine-2,7-diamine;871266-93-2;7-N-(4-methoxyphenyl)-2-N-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-diamine;DTXSID60470326

Suppliers and Price of N7-(4-Methoxyphenyl)-N2-phenylthiazolo[5,4-d]pyrimidine-2,7-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-7-(4-METHOXYPHENYL)-N-2-PHENYLTHIAZOLO-[5,4-D]-PYRIMIDINE-2,7-DIAMINE 95.00%
5MG
$ 505.71

Total 4 raw suppliers

Chemical Property of N7-(4-Methoxyphenyl)-N2-phenylthiazolo[5,4-d]pyrimidine-2,7-diamine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:562.767°C at 760 mmHg
Flash Point:294.151°C
PSA：100.20000
Density:1.404g/cm³
LogP:4.72810
XLogP3:4.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:349.09973129
Heavy Atom Count:25
Complexity:414

Purity/Quality:

97% ^*data from raw suppliers

N-7-(4-METHOXYPHENYL)-N-2-PHENYLTHIAZOLO-[5,4-D]-PYRIMIDINE-2,7-DIAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)NC2=C3C(=NC=N2)SC(=N3)NC4=CC=CC=C4

Technology Process of N7-(4-Methoxyphenyl)-N2-phenylthiazolo[5,4-d]pyrimidine-2,7-diamine

There total 2 articles about N7-(4-Methoxyphenyl)-N2-phenylthiazolo[5,4-d]pyrimidine-2,7-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 871266-78-3
(7-chloro[1,3]thiazolo[5,4-d]pyrimidin-2-yl)(phenyl)amine

: 104-94-9
4-methoxy-aniline

: 871266-93-2
N⁷-(4-methoxyphenyl)-N²-phenyl[1,3]thiazolo[5,4-d]pyrimidine-2,7-diamine

Guidance literature:: With acetic acid; In 1,4-dioxane; at 150 ℃; for 0.666667h; microwave irradiation;
DOI:10.1021/jo0517702

Reference yield:

: 103-72-0
phenyl isothiocyanate

: 871266-93-2
N⁷-(4-methoxyphenyl)-N²-phenyl[1,3]thiazolo[5,4-d]pyrimidine-2,7-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / Cs₂CO₃ / acetonitrile / 16 h / 50 °C

2: 86 percent / acetic acid / dioxane / 0.67 h / 150 °C / microwave irradiation

With caesium carbonate; acetic acid; In 1,4-dioxane; acetonitrile;
DOI:10.1021/jo0517702