2-(4-METHOXY-BENZENESULFONYLAMINO)-3-METHYL-BUTYRIC ACID

Base Information

• Chemical Name: 2-(4-METHOXY-BENZENESULFONYLAMINO)-3-METHYL-BUTYRIC ACID
• CAS No.: 197965-89-2
• Molecular Formula: C12H17NO5S
• Molecular Weight: 287.337
• Hs Code.: 2935009090
• Mol file: 197965-89-2.mol

Synonyms:TIMTEC-BB SBB012264;2-(4-METHOXY-BENZENESULFONYLAMINO)-3-METHYL-BUTYRIC ACID;2-([(4-METHOXYPHENYL)SULFONYL]AMINO)-3-METHYLBUTANOIC ACID;AKOS BC-3176

Chemical Property of 2-(4-METHOXY-BENZENESULFONYLAMINO)-3-METHYL-BUTYRIC ACID

Chemical Property:

• PSA: 101.08000
• LogP: 2.55440

Purity/Quality:

98%min ^*data from raw suppliers

2-(4-Methoxy-benzenesulfonylamino)-3-methyl-butyric acid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-METHOXY-BENZENESULFONYLAMINO)-3-METHYL-BUTYRIC ACID

There total 2 articles about 2-(4-METHOXY-BENZENESULFONYLAMINO)-3-METHYL-BUTYRIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D,L-valine (516-06-3,25609-85-2,7004-03-7,921-10-8) + 4-methoxy-phenyl-sulphonyl chloride (98-68-0) → N-((4-methoxyphenyl)sulfonyl)valine (197965-89-2)

Guidance literature:

With triethylamine; In 1,4-dioxane; water; Ambient temperature;

DOI:10.1021/jm960871c

Reference yield:

→ N-((4-methoxyphenyl)sulfonyl)valine (197965-89-2)

Guidance literature:

Reference yield: 60.0%

para-xylene (106-42-3) + N-((4-methoxyphenyl)sulfonyl)valine (197965-89-2) → 1-methoxy-4-((4-methylbenzyl)sulfonyl)benzene (108545-54-6)

Guidance literature:

With sodium persulfate; silver fluoride; In water; acetonitrile; at 100 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1246/BCSJ.20200393

upstream raw materials:

D,L-valine

4-methoxy-phenyl-sulphonyl chloride

Downstream raw materials:

2(R)-(4-methoxybenzenesulfonylamino)-3-methylbutyric acid tert-butyl ester

2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-3-methyl-butyric acid

2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-3-methyl-butyric acid tert-butyl ester

1-methoxy-4-((4-methylbenzyl)sulfonyl)benzene