(5S)-5-Methylpropyl-3-Morpholinone

Base Information

Chemical Name:(5S)-5-Methylpropyl-3-Morpholinone
CAS No.:101250-44-6
Molecular Formula:C8H15NO2
Molecular Weight:157.2102
Hs Code.:
Mol file:101250-44-6.mol

Synonyms:(5S)-5-Methylpropyl-3-Morpholinone;(5S)-5-(2-methylpropyl)morpholin-3-one;(5S)-5-Isobutyl-3-morpholinone

Suppliers and Price of (5S)-5-Methylpropyl-3-Morpholinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

aablocks
3-Morpholinone,5-(2-methylpropyl)-,(5S)- 95.0%
1g
$ 410.00

aablocks
3-Morpholinone,5-(2-methylpropyl)-,(5S)- 95.0%
500mg
$ 300.00

aablocks
3-Morpholinone,5-(2-methylpropyl)-,(5S)- 95.0%
250mg
$ 180.00

aablocks
3-Morpholinone,5-(2-methylpropyl)-,(5S)- 95.0%
100mg
$ 140.00

Total 4 raw suppliers

Chemical Property of (5S)-5-Methylpropyl-3-Morpholinone

Chemical Property:

PSA：38.33000
LogP:0.87630

Purity/Quality:

>95%,>98%e.e. ^*data from raw suppliers

3-Morpholinone,5-(2-methylpropyl)-,(5S)- 95.0% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5S)-5-Methylpropyl-3-Morpholinone

There total 4 articles about (5S)-5-Methylpropyl-3-Morpholinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 7533-40-6,14438-11-0
(S)-2-amino-4-methylpentan-1-ol

: 105-39-5
chloroacetic acid ethyl ester

: 101250-44-6
(S)-5-(2-methylpropyl)-3-morpholinone

Guidance literature:: With sodium hydride; In tetrahydrofuran; paraffin; 1.) 25 deg C, 30 min, 2.) 25 deg C, 30 min; reflux, 3 h;
DOI:10.1021/jo960496w

Reference yield: 24.0%

: 101250-43-5
(S)-2-chloro-N-<1-(hydroxymethyl)-3-methylbutyl>acetamide

: 101250-44-6
(S)-5-(2-methylpropyl)-3-morpholinone

Guidance literature:: With sodium hydride; In tetrahydrofuran; for 14h; Ambient temperature;
DOI:10.1021/jm00156a012

Reference yield:

: 7533-40-6,14438-11-0
(S)-2-amino-4-methylpentan-1-ol

: 101250-44-6
(S)-5-(2-methylpropyl)-3-morpholinone

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / NaOAc / acetone; H₂O / 2 h / Ambient temperature

2: 24 percent / NaH / tetrahydrofuran / 14 h / Ambient temperature

With sodium acetate; sodium hydride; In tetrahydrofuran; water; acetone;
DOI:10.1021/jm00156a012