6-Methoxy-5-(4-methyl-1H-imidazol-1-YL)pyridin-2-amine

Base Information

Chemical Name:6-Methoxy-5-(4-methyl-1H-imidazol-1-YL)pyridin-2-amine
CAS No.:1232039-16-5
Molecular Formula:C₁₀H₁₂N₄O
Molecular Weight:204.231
Hs Code.:
DSSTox Substance ID:DTXSID30695089
Wikidata:Q82624101

Synonyms:6-METHOXY-5-(4-METHYL-1H-IMIDAZOL-1-YL)PYRIDIN-2-AMINE;1232039-16-5;6-methoxy-5-(4-methylimidazol-1-yl)pyridin-2-amine;6-Methoxy-5-(4-methylimidazol-1-yl)pyridin-2-ylamine;SCHEMBL512985;DTXSID30695089;WVKMUAJRHBKDSN-UHFFFAOYSA-N;MFCD18711537;AS-35909;CS-0172182;A925845;6-Methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-ylamine

Suppliers and Price of 6-Methoxy-5-(4-methyl-1H-imidazol-1-YL)pyridin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 6-Methoxy-5-(4-methyl-1H-imidazol-1-YL)pyridin-2-amine

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:204.10111102
Heavy Atom Count:15
Complexity:214

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN(C=N1)C2=C(N=C(C=C2)N)OC

Technology Process of 6-Methoxy-5-(4-methyl-1H-imidazol-1-YL)pyridin-2-amine

There total 1 articles about 6-Methoxy-5-(4-methyl-1H-imidazol-1-YL)pyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89284-11-7
5,6-dibromopyridin-2-ylamine

: 1232039-16-5
6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium / 4 h / -20 - 0 °C

1.2: 24 h / 120 °C / Sealed tube

2.1: caesium carbonate / copper(l) iodide / N,N-dimethyl-formamide / 2 h / 140 - 150 °C / Inert atmosphere; Microwave

With sodium; caesium carbonate; copper(l) iodide; In N,N-dimethyl-formamide;

Reference yield: 87.0%

: 1232039-16-5
6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-amine

: 2-chloro-8-methyl-7-(o-tolyl)-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazine

: N-(6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl)-8-methyl-7-(o-tolyl)-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-2-amine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 120 ℃; for 16h; Inert atmosphere; Sealed tube;

Reference yield: 63.4%

: 1232039-16-5
6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-amine

: 1239719-55-1
4-bromo-2-(4-fluorophenyl)-1-methyl-1H-benzimidazole

: 1240608-99-4
[2-(4-fluorophenyl)-1-methyl-1H-benzoimidazol-4-yl]-[6-methoxy-5-(4-methylimidazol-1-yl)pyridin-2-yl]amine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; XPhos; In tert-butyl alcohol; at 100 ℃; for 3h; Inert atmosphere;
DOI:10.1021/jm201710f