Pyrrolo[2,3-b]pyridin-1-yl-acetic acid

Base Information

Chemical Name:Pyrrolo[2,3-b]pyridin-1-yl-acetic acid
CAS No.:1048913-13-8
Molecular Formula:C9H8N2O2
Molecular Weight:176.175
Hs Code.:2933990090
Mol file:1048913-13-8.mol

Synonyms:Pyrrolo[2,3-b]pyridin-1-yl-acetic acid

Suppliers and Price of Pyrrolo[2,3-b]pyridin-1-yl-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-(1H-Pyrrolo[2,3-b]pyridin-1-yl)acetic acid >95%
1g
$ 419.00

Matrix Scientific
2-(1H-Pyrrolo[2,3-b]pyridin-1-yl)acetic acid >95%
500mg
$ 272.00

Crysdot
2-(1H-Pyrrolo[2,3-b]pyridin-1-yl)aceticacid 95+%
1g
$ 510.00

Chemenu
2-(1H-Pyrrolo[2,3-b]pyridin-1-yl)aceticacid 95%+
5g
$ 1597.00

Chemenu
2-(1H-Pyrrolo[2,3-b]pyridin-1-yl)aceticacid 95%+
1g
$ 577.00

Apolloscientific
2-(1H-Pyrrolo[2,3-b]pyridin-1-yl)aceticacid 95%
1g
$ 520.00

Apolloscientific
2-(1H-Pyrrolo[2,3-b]pyridin-1-yl)aceticacid 95%
500mg
$ 360.00

Alichem
2-(1H-Pyrrolo[2,3-b]pyridin-1-yl)aceticacid
1g
$ 411.84

Total 13 raw suppliers

Chemical Property of Pyrrolo[2,3-b]pyridin-1-yl-acetic acid

Chemical Property:

Melting Point:169～170℃
Boiling Point:405.0±25.0 °C(Predicted)
PKA:2.07±0.10(Predicted)
PSA：55.12000
Density:1.35±0.1 g/cm3(Predicted)
LogP:1.12090

Purity/Quality:

99%, ^*data from raw suppliers

2-(1H-Pyrrolo[2,3-b]pyridin-1-yl)acetic acid >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1H-?Pyrrolo[2,?3-?b]?pyridin-?1-?ylacetic Acid is an analog of 7-Azaindole and can be used as a novel inhibitor of glycogen phosphorylase.

Technology Process of Pyrrolo[2,3-b]pyridin-1-yl-acetic acid

There total 2 articles about Pyrrolo[2,3-b]pyridin-1-yl-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1048913-05-8
ethyl 2-pyrrolo[2,3-b]pyridin-1-ylacetate

: 1048913-13-8
2-(1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 271-63-6
7-Azaindole

: 1048913-13-8
2-(1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 60 °C

2: water; lithium hydroxide / tetrahydrofuran / 20 °C

With water; potassium carbonate; lithium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield: 79.0%

: 1048913-13-8
2-(1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid

: 1253936-65-0
1-(2-bromo-4-(trifluoromethyl)phenyl)piperazine

: 1253936-66-1
1-[4-(2-bromo-4-trifluoromethyl-phenyl)-piperazin-1-yl]-2-pyrrolo[2,3-b]pyridin-1-yl-ethanone

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In dichloromethane; at 20 ℃; for 2h;