7-Azaindole

Base Information

Chemical Name:7-Azaindole
CAS No.:271-63-6
Molecular Formula:C7H6N2
Molecular Weight:118.138
Hs Code.:29339990
European Community (EC) Number:205-981-0
NSC Number:77951,67063
UNII:QX4465NR9T
DSSTox Substance ID:DTXSID3075046
Nikkaji Number:J49.676F
Wikipedia:7-azaindole
Wikidata:Q27287542
ChEMBL ID:CHEMBL389685
Mol file:271-63-6.mol

Synonyms:7-azaindole;7-azaindole dimer

Suppliers and Price of 7-Azaindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Azaindole
50g
$ 100.00

TRC
7-Azaindole
25g
$ 85.00

TCI Chemical
1H-Pyrrolo[2,3-b]pyridine >98.0%(GC)(T)
25g
$ 100.00

TCI Chemical
1H-Pyrrolo[2,3-b]pyridine >98.0%(GC)(T)
5g
$ 21.00

SynQuest Laboratories
7-Azaindole 98%
5 g
$ 16.00

SynQuest Laboratories
7-Azaindole 98%
25 g
$ 40.00

SynChem
7-AZAINDOLE 95%
25 g
$ 45.00

Sigma-Aldrich
7-Azaindole 98%
5g
$ 70.50

Sigma-Aldrich
7-Azaindole 98%
1g
$ 31.40

Sigma-Aldrich
7-Azaindole 95%
1g
$ 30.60

Total 222 raw suppliers

Chemical Property of 7-Azaindole

Chemical Property:

Appearance/Colour:brown-cyrstalline solid
Vapor Pressure:0.0094mmHg at 25°C
Melting Point:105-107 °C(lit.)
Refractive Index:1.696
Boiling Point:273.8 °C at 760 mmHg
PKA:7.69±0.20(Predicted)
Flash Point:124.8 °C
PSA：28.68000
Density:1.242 g/cm³
LogP:1.56290
Storage Temp.:Refrigerator
Solubility.:Chloroform, Methanol
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:118.053098200
Heavy Atom Count:9
Complexity:103

Purity/Quality:

99% ^*data from raw suppliers

7-Azaindole ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xi,Xn
Statements: 36-41-37/38-22
Safety Statements: 39-26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(NC=C2)N=C1
Uses 7-Azaindole is imidazolinone derivatives as CGRP receptor antagonists used in the treatment.A heterocyclic molecule that can be utilized as a pharmaceutical building block.Starting material in a recent synthesis of azaserotonin.

Technology Process of 7-Azaindole

There total 50 articles about 7-Azaindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 138343-75-6
tert-butyl (3-methylpyridin-2-yl)carbamate

: 271-63-6
7-Azaindole

Guidance literature:: tert-butyl (3-methylpyridin-2-yl)carbamate; With n-butyllithium; N,N-dimethyl-formamide; In tetrahydrofuran; at 0 ℃;

With hydrogenchloride; In tetrahydrofuran; water; at 50 ℃;
DOI:10.1021/ol900150u

Reference yield: 100.0%

: 138343-77-8
1-(tert-butoxycarbonyl)-1H-pyrrolo<2,3-b>pyridine

: 271-63-6
7-Azaindole

Guidance literature:: With sodium carbonate; In 1,2-dimethoxyethane; water; for 20h; Heating;
DOI:10.1016/j.tetlet.2006.09.129

Reference yield: 99.1%

: 74-83-9
methyl bromide

: 138343-75-6
tert-butyl (3-methylpyridin-2-yl)carbamate

: 271-63-6
7-Azaindole

Guidance literature:: methyl bromide; tert-butyl (3-methylpyridin-2-yl)carbamate; In diethyl ether; at 0 ℃; for 4h;

With N,N-dimethyl-formamide; In diethyl ether; at 0 ℃; for 0.5h; Concentration;