2-(2,3-Dihydrobenzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

• Chemical Name: 2-(2,3-Dihydrobenzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS No.: 937591-69-0
• Molecular Formula: C14H19BO3
• Molecular Weight: 246.114
• Hs Code.: 2934999090
• European Community (EC) Number: 969-291-8
• DSSTox Substance ID: DTXSID40587820
• Wikidata: Q82480313
• Mol file: 937591-69-0.mol

Synonyms:937591-69-0;2-(2,3-Dihydrobenzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2,3-Dihydrobenzofuran-5-boronic acid pinacol ester;2-(2,3-dihydro-1-benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1-benzofuran;SCHEMBL4427556;DTXSID40587820;RWJUUXWJBMIGKA-UHFFFAOYSA-N;(2,3-DIHYDROBENZOFURAN-5-YL)BORONIC ACID PINACOL ESTER;MFCD09743046;AKOS015999413;DS-17698;DB-340529;CS-0041481;EN300-212708;A859650;Z1336745212;2-(2 pound not3-Dihydrobenzofuran-5-yl)-4 pound not4 pound not5 pound not5-tetramethyl-1 pound not3 pound not2-dioxaborolane

Chemical Property of 2-(2,3-Dihydrobenzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

• PSA: 27.69000
• LogP: 1.92070
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 246.1427246
• Heavy Atom Count: 18
• Complexity: 313

Purity/Quality:

97% ^*data from raw suppliers

2,3-Dihydrobenzofuran-5-boronicacidpinacolester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)OCC3

Technology Process of 2-(2,3-Dihydrobenzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 5 articles about 2-(2,3-Dihydrobenzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

→ 2‐(2,3‐dihydro‐1‐benzofuran‐5‐yl)‐4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolane (937591-69-0)

Guidance literature:

Reference yield:

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran (519054-55-8) → 2‐(2,3‐dihydro‐1‐benzofuran‐5‐yl)‐4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolane (937591-69-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 40 ℃; for 48h; under 775.743 Torr;

Reference yield:

5-bromo-2,3-dihydrobenzo[b]furan (66826-78-6) + bis(pinacol)diborane (73183-34-3) → 2‐(2,3‐dihydro‐1‐benzofuran‐5‐yl)‐4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolane (937591-69-0)

Guidance literature:

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In 1,4-dioxane; at 90 ℃; for 16h;

upstream raw materials:

bis(pinacol)diborane

5-bromobenzofuran

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran

5-bromo-2,3-dihydrobenzo[b]furan

Downstream raw materials:

5-methyl-2,3-dihydrobenzofuran