(S)-2-((tert-Butoxycarbonyl)amino)-4-methoxybutanoic acid

Base Information

Chemical Name:(S)-2-((tert-Butoxycarbonyl)amino)-4-methoxybutanoic acid
CAS No.:104839-08-9
Molecular Formula:C10H19NO5
Molecular Weight:233.265
Hs Code.:
DSSTox Substance ID:DTXSID201209241
Mol file:104839-08-9.mol

Synonyms:104839-08-9;N-Boc-O-methyl-L-homoserine;Boc-homoSer(Me)-OH;(S)-2-((tert-Butoxycarbonyl)amino)-4-methoxybutanoic acid;N-(tert-butoxycarbonyl)-O-methyl-L-homoserine;Boc-Hse(Me)-OH;(2S)-4-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid;Boc O-methylhomoserine;SCHEMBL953453;ITXBKRHPHSTADP-ZETCQYMHSA-N;DTXSID201209241;MFCD00270513;AKOS027326761;CS-0416098;F79802;N-[(1,1-Dimethylethoxy)carbonyl]-O-methyl-L-homoserine;N-{[(1,1-dimethylethyl)oxy]carbonyl}-O-methylhomoserine

Suppliers and Price of (S)-2-((tert-Butoxycarbonyl)amino)-4-methoxybutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Activate Scientific
N-Boc-O-methyl-L-homoserine 95% ee
1 g
$ 529.00

Acrotein
N-Boc-O-methyl-L-homoserine 97%
0.25g
$ 192.50

Total 5 raw suppliers

Chemical Property of (S)-2-((tert-Butoxycarbonyl)amino)-4-methoxybutanoic acid

Chemical Property:

Boiling Point:384.1±37.0 °C(Predicted)
PKA:3.83±0.10(Predicted)
PSA：114.45000
Density:1.125±0.06 g/cm3(Predicted)
LogP:5.03360
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:233.12632271
Heavy Atom Count:16
Complexity:246

Purity/Quality:

98%+ ^*data from raw suppliers

N-Boc-O-methyl-L-homoserine 95% ee ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CCOC)C(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CCOC)C(=O)O

Technology Process of (S)-2-((tert-Butoxycarbonyl)amino)-4-methoxybutanoic acid

There total 2 articles about (S)-2-((tert-Butoxycarbonyl)amino)-4-methoxybutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 3311-01-1,57906-58-8
HSer(γ-OMe)

: 104839-08-9
(S)-2-((tert-butoxycarbonyl)amino)-4-methoxybutanoic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; at 20 ℃;
DOI:10.1016/j.bmcl.2003.09.088

Reference yield:

: 41088-86-2
L-2-(tert-butyloxycarbonylamino)-4-hydroxybutyric acid

: 74-88-4
methyl iodide

: 104839-08-9
(S)-2-((tert-butoxycarbonyl)amino)-4-methoxybutanoic acid

Guidance literature:: L-2-(tert-butyloxycarbonylamino)-4-hydroxybutyric acid; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.25h; Inert atmosphere;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jm500602h

Reference yield: 75.0%

: 95-83-0
4-Chloro-1,2-phenylenediamine

: 104839-08-9
(S)-2-((tert-butoxycarbonyl)amino)-4-methoxybutanoic acid

: 864296-81-1
(S)-2-(tert-butoxycarbonyl-amino)-4-methoxy-butyric acid 2-amino-5-chloro-phenyl amide

: 864296-80-0
(S)-2-(tert-butoxycarbonyl-amino)-4-methoxy-butyric acid 2-amino-4-chloro-phenyl amide

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In tetrahydrofuran; at 20 ℃; for 16h;