OCTAKIS-6-IODO-6-DEOXY-GAMMA-CYCLODEXTRIN

Base Information

• Chemical Name: OCTAKIS-6-IODO-6-DEOXY-GAMMA-CYCLODEXTRIN
• CAS No.: 168296-33-1
• Molecular Formula: C48 H72 I8 O32
• Molecular Weight: 2176.33
• Hs Code.: 9999999999
• Mol file: 168296-33-1.mol

Synonyms:Octakis-6-iodo-6-deoxy-γ-cyclodextrin

Chemical Property of OCTAKIS-6-IODO-6-DEOXY-GAMMA-CYCLODEXTRIN

Chemical Property:

• Melting Point: 208-212°C
• PKA: 11.60±0.70(Predicted)
• PSA: 471.36000
• Density: 2.245±0.06 g/cm3(Predicted)
• LogP: -5.86480
• Solubility.: Soluble in DMF, DMSO. Insoluble in water, methanol, chloroform.

Purity/Quality:

98%min ^*data from raw suppliers

6A,6B,6C,6D,6E,6F,6G,6H-Octadeoxy-6A,6B,6C,6D,6E,6F,6G,6H-octaiodo-γ-cyclodextrin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 6A,6B,6C,6D,6E,6F,6G,6H-Octadeoxy-6A,6B,6C,6D,6E,6F,6G,6H-octaiodo-γ-cyclodextrin is a useful chemical compound for preparation of isothiocyanates and cyclic thiocarbamates of trehalose sucrose and cyclomaltooligosaccharides.

Technology Process of OCTAKIS-6-IODO-6-DEOXY-GAMMA-CYCLODEXTRIN

There total 2 articles about OCTAKIS-6-IODO-6-DEOXY-GAMMA-CYCLODEXTRIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

cyclomaltooctaose (17465-86-0) → octakis(6-deoxy-6-iodo)-γ-cyclodextrin (168296-33-1)

Guidance literature:

With tetraethylammonium iodide; 4-pyrrolidin-1-ylpyridine; ethanaminium,N-(difluoro-λ⁴-sulfanylidene)-N-ethyl-,tetrafluoroborate; In N,N-dimethyl-formamide; at 20 ℃; regioselective reaction;

DOI:10.1055/s-0033-1339762

Reference yield:

C80H104I8O48 → octakis(6-deoxy-6-iodo)-γ-cyclodextrin (168296-33-1)

Guidance literature:

With methanol; sodium methylate; for 96h;

DOI:10.1002/asia.201100217

Reference yield: 100.0%

octakis(6-deoxy-6-iodo)-γ-cyclodextrin (168296-33-1) → 6A,6B,6C,6D,6E,6F,6G,6H-octaazido-6A,6B,6C,6D,6E,6F,6G,6H-octadeoxy-γ-cyclodextrin (156297-61-9)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 80 ℃;

DOI:10.3390/molecules27041163

upstream raw materials:

cyclomaltooctaose

Downstream raw materials:

6^A,6^B,6^C,6^D,6^E,6^F,6^G,6^H-octaazido-6^A,6^B,6^C,6^D,6^E,6^F,6^G,6^H-octadeoxy-γ-cyclodextrin