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Cas No: 17465-86-0
No Data 1 Kilogram 100 Metric Ton/Year Wuhan PharmChem Co.,Ltd Contact Supplier
Cyclooctapentylose Manufacturer/High quality/Best price/In stock
Cas No: 17465-86-0
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High purity Various Specifications gamma-Cyclodextrin CAS:17465-86-0
Cas No: 17465-86-0
USD $ 100.0-500.0 / Gram 1 Gram 99999 Gram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
High quality Gamma-Cyclodextrin supplier in China
Cas No: 17465-86-0
No Data 1 Metric Ton 30 Metric Ton/Month Simagchem Corporation Contact Supplier
Manufacturer supply Cyclooctapentylose CAS 17465-86-0 with attractive price
Cas No: 17465-86-0
USD $ 10.0-10.0 / Kilogram 1 Kilogram 30 Metric Ton/Month Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
Good quantity γ(gamma)-Cyclodextrin factory
Cas No: 17465-86-0
No Data 1 Kilogram 1 Metric Ton/Month Hangzhou Think Chemical Co. Ltd Contact Supplier
Cas No: 17465-86-0
No Data 25 Kilogram 1500 Metric Ton/Year Hefei TNJ chemical industry co.,ltd Contact Supplier
Factory Supply Cyclooctapentylose
Cas No: 17465-86-0
No Data 1 1 Ality Chemical Corporation Contact Supplier
Factory Price API 99% Cyclooctapentylose 17465-86-0 GMP Manufacturer
Cas No: 17465-86-0
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Cas No: 17465-86-0
No Data 100 Kilogram Metric Ton/Day HANGZHOU CLAKE BIOTECH CO.,LTD Contact Supplier

17465-86-0 Usage

Chemical Properties

Different sources of media describe the Chemical Properties of 17465-86-0 differently. You can refer to the following data:
1. White powder or crystal
2. Cyclodextrins occur as white, practically odorless, fine crystalline powders, having a slightly sweet taste. Some cyclodextrin derivatives occur as amorphous powders.


Different sources of media describe the Uses of 17465-86-0 differently. You can refer to the following data:
1. A molecule used to solublize non-polar molecules such a cholesterol for use in cell culture.
2. γ-Cyclodextrin can be used as a precursor for the synthesis of: Octakis-(2,3-di-O-methyl-6-O-carboxymethyl)-γ-cyclodextrin sodium salt (ODMCM). ODMCM is used in capillary electrophoresis as a chiral resolving agent.Water-soluble cyclodextrin thioethers derivatives for the transportation of hydrophobic drugs.
3. γ-Cyclodextrin (γ-CD), a water-soluble cyclic oligosaccharide consisting of eight α-(1,4)-linked glucopyranose subunits, can be used in a wide range of applications including:Synthesis of renewable and biocompatible metal-organic frameworks.Formation of inclusion complexes with a variety of guest molecules to increase their solubility in water and other polar solvents.Synthesis of γ-CD based nanogels and dendrimers as carriers and stabilizers for drug delivery applications.

Production Methods

Cyclodextrins are manufactured by the enzymatic degradation of starch using specialized bacteria. For example, β-cyclodextrin is produced by the action of the enzyme cyclodextrin glucosyltransferase upon starch or a starch hydrolysate. An organic solvent is used to direct the reaction that produces β-cyclodextrin, and to prevent the growth of microorganisms during the enzymatic reaction. The insoluble complex of β-cyclodextrin and organic solvent is separated from the noncyclic starch, and the organic solvent is removed in vacuo so that less than 1 ppm of solvent remains in the β-cyclodextrin. The β-cyclodextrin is then carbon treated and crystallized from water, dried, and collected.

General Description

Cyclodextrins belongs to the family of cyclic α-1,4-glucans and is made of glucose units. This molecule has a shape of a hollow cone. It possesses a hydrophilic external and hydrophobic internal surface, because of which cyclodextrins can form inclusion complexes. γ-Cyclodextrin is extensively used in food and pharmaceutical industries. Cyclodextrins are obtained by the enzymatic conversion of starch/starch derivatives by cyclodextrin glycosyltransferase.

Flammability and Explosibility


Pharmaceutical Applications

Cyclodextrins are ‘bucketlike’ or ‘conelike’ toroid molecules, with a rigid structure and a central cavity, the size of which varies according to the cyclodextrin type. The internal surface of the cavity is hydrophobic and the outside of the torus is hydrophilic; this is due to the arrangement of hydroxyl groups within the molecule. This arrangement permits the cyclodextrin to accommodate a guest molecule within the cavity, forming an inclusion complex.Cyclodextrins may be used to form inclusion complexes with a variety of drug molecules, resulting primarily in improvements to dissolution and bioavailability owing to enhanced solubility and improved chemical and physical stability.Cyclodextrin inclusion complexes have also been used to mask the unpleasant taste of active materials and to convert a liquid substance into a solid material. γ-cyclodextrin has the largest cavity and can be used to form inclusion complexes with large molecules;it has low toxicity and enhanced water solubility. In parenteral formulations, cyclodextrins have been used to produce stable and soluble preparations of drugs that would otherwise have been formulated using a nonaqueous solvent. In eye drop formulations, cyclodextrins form water-soluble complexes with lipophilic drugs such as corticosteroids. They have been shown to increase the water solubility of the drug; to enhance drug absorption into the eye; to improve aqueous stability; and to reduce local irritation.Cyclodextrins have also been used in the formulation of solutions,suppositories, and cosmetics.


Cyclodextrins are starch derivatives and are mainly used in oral and parenteral pharmaceutical formulations. They are also used in topical and ophthalmic formulations. Cyclodextrins are also used in cosmetics and food products, and are generally regarded as essentially nontoxic and nonirritant materials. However, when administered parenterally, β-cyclodextrin is not metabolized but accumulates in the kidneys as insoluble cholesterol complexes, resulting in severe nephrotoxicity. Cyclodextrin administered orally is metabolized by microflora in the colon, forming the metabolites maltodextrin, maltose, and glucose; these are themselves further metabolized before being finally excreted as carbon dioxide and water. Although a study published in 1957 suggested that orally administered cyclodextrins were highly toxic, more recent animal toxicity studies in rats and dogs have shown this not to be the case, and cyclodextrins are now approved for use in food products and orally administered pharmaceuticals in a number of countries. Cyclodextrins are not irritant to the skin and eyes, or upon inhalation. There is also no evidence to suggest that cyclodextrins are mutagenic or teratogenic. γ-Cyclodextrin LD50 (rat, IP): 4.6 g/kg LD50 (rat ,IV): 4.0 g/kg LD50 (rat, oral): 8.0 g/kg


Cyclodextrins should be stored in a tightly sealed container, in a cool, dry place.Cyclodextrins are stable in the solid state if protected from high humidity.

Regulatory Status

Included in the FDA Inactive Ingredients Database: α-cyclodextrin (injection preparations); β-cyclodextrin (oral tablets, topical gels); γ-cyclodextrin (IV injections). Included in the Canadian List of Acceptable Non-medicinal Ingredients (stabilizing agent; solubilizing agent ); and in oral and rectal pharmaceutical formulations licensed in Europe, Japan, and the USA.

Check Digit Verification of cas no

The CAS Registry Mumber 17465-86-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,4,6 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 17465-86:
130 % 10 = 0
So 17465-86-0 is a valid CAS Registry Number.

17465-86-0 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
TCI America (C0869)  γ-Cyclodextrin  >99.0%(HPLC) 17465-86-0 5g 480.00CNY Detail
TCI America (C0869)  γ-Cyclodextrin  >99.0%(HPLC) 17465-86-0 25g 1,280.00CNY Detail
TCI America (C0869)  γ-Cyclodextrin  >99.0%(HPLC) 17465-86-0 100g 3,890.00CNY Detail
Sigma (C4892)  γ-Cyclodextrin  ≥98% 17465-86-0 C4892-1G 3,309.93CNY Detail
Sigma (C4892)  γ-Cyclodextrin  ≥98% 17465-86-0 C4892-5G 12,671.10CNY Detail
Sigma-Aldrich (G0150000)  Gammacyclodextrin   17465-86-0 G0150000 1,880.19CNY Detail
USP (1154591)  GammaCyclodextrin  United States Pharmacopeia (USP) Reference Standard 17465-86-0 1154591-200MG 4,326.66CNY Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017


1.1 GHS Product identifier

Product name γ-cyclodextrin

1.2 Other means of identification

Product number -
Other names cyclomaltooctaose

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. CBI
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

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