2'-Cyano-2'-deoxyarabinofuranosylcytosine

Base Information

Chemical Name:2'-Cyano-2'-deoxyarabinofuranosylcytosine
CAS No.:134665-72-8
Molecular Formula:C10H12 N4 O4 . Cl H
Molecular Weight:288.691
Hs Code.:
UNII:VSS4ZDZ2IE
DSSTox Substance ID:DTXSID30158861
NCI Thesaurus Code:C150430
ChEMBL ID:CHEMBL1204346
Mol file:134665-72-8.mol

Synonyms:2'-cyano-2'-deoxyarabinofuranosylcytosine;2'-cyano-2'deoxy-1-beta-D-arabinofuranosylcytosine;CNDAC

Suppliers and Price of 2'-Cyano-2'-deoxyarabinofuranosylcytosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
CNDACHCl >98%
250 mg
$ 1000.00

DC Chemicals
CNDACHCl >98%
100 mg
$ 600.00

DC Chemicals
CNDACHCl >98%
1 g
$ 2100.00

ChemScene
CNDAChydrochloride 99.53%
100mg
$ 2250.00

ChemScene
CNDAChydrochloride 99.53%
50mg
$ 1650.00

ChemScene
CNDAChydrochloride 99.53%
5mg
$ 350.00

Total 11 raw suppliers

Chemical Property of 2'-Cyano-2'-deoxyarabinofuranosylcytosine

Chemical Property:

Boiling Point:596.9°Cat760mmHg
Flash Point:314.8°C
PSA：135.38000
Density:g/cm³
LogP:-0.63972
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:288.0625326
Heavy Atom Count:19
Complexity:466

Purity/Quality:

97% ^*data from raw suppliers

CNDACHCl >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)C#N.Cl
Isomeric SMILES:C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)C#N.Cl

Technology Process of 2'-Cyano-2'-deoxyarabinofuranosylcytosine

There total 2 articles about 2'-Cyano-2'-deoxyarabinofuranosylcytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 135598-72-0
N⁴-acetyl-1-(2-C-cyano-2-deoxy-β-D-arabinofuranosyl)cytosine

: 134665-72-8
2'-C-cyano-2'-deoxy-1-β-D-arabinofuranosylcytosine hydrochloride

Guidance literature:: With hydrogenchloride; In methanol; at 20 - 25 ℃; for 1h;

Reference yield:

: 135598-71-9
N⁴-acetyl-1-<2-C-cyano-2-deoxy-3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl>cytosine

: 134665-72-8
2'-C-cyano-2'-deoxy-1-β-D-arabinofuranosylcytosine hydrochloride

Guidance literature:: With hydrogenchloride; water; In methanol; at 53 - 60 ℃;

Reference yield: 28.0%

: 134665-72-8
2'-C-cyano-2'-deoxy-1-β-D-arabinofuranosylcytosine hydrochloride

: 71-30-7
Cytosine

: 1,4-anhydro-2-C-cyano-2-deoxy-D-erythropent-1-enitol

: 2'-C-cyano-2'-deoxy-1-β-D-ribo-pentofuranosylcytosine

Guidance literature:: With Tris-HCl buffer; at 37 ℃; for 6h; Rate constant; Mechanism; var. salt concentration and pH of buffer;
DOI:10.1021/jm00017a023