0,11-DIMETHOXY-6-METHYL-5,6-DIHYDRO-4H-DIBENZO[DE,G]QUINOLINE

Base Information

Chemical Name:0,11-DIMETHOXY-6-METHYL-5,6-DIHYDRO-4H-DIBENZO[DE,G]QUINOLINE
CAS No.:18605-43-1
Molecular Formula:C₁₉H₁₉NO₂
Molecular Weight:293.365
Hs Code.:2933990090
Mol file:18605-43-1.mol

Synonyms:0,11-DIMETHOXY-6-METHYL-5,6-DIHYDRO-4H-DIBENZO[DE,G]QUINOLINE

Suppliers and Price of 0,11-DIMETHOXY-6-METHYL-5,6-DIHYDRO-4H-DIBENZO[DE,G]QUINOLINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
10,11-DIMETHOXY-6-METHYL-5,6-DIHYDRO-4H-DIBENZO[DE,G]QUINOLINE 95.00%
5MG
$ 501.27

Total 1 raw suppliers

Chemical Property of 0,11-DIMETHOXY-6-METHYL-5,6-DIHYDRO-4H-DIBENZO[DE,G]QUINOLINE

Chemical Property:

PSA：21.70000
LogP:4.06750

Purity/Quality:: 10,11-DIMETHOXY-6-METHYL-5,6-DIHYDRO-4H-DIBENZO[DE,G]QUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 0,11-DIMETHOXY-6-METHYL-5,6-DIHYDRO-4H-DIBENZO[DE,G]QUINOLINE

There total 19 articles about 0,11-DIMETHOXY-6-METHYL-5,6-DIHYDRO-4H-DIBENZO[DE,G]QUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38291-33-7
(R)-10,11-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

: 61013-20-5
10,11-dimethoxy-6-methyl-6H-dibenzo[de,g]quinoline

: 18605-43-1
10,11-dimethoxy-6-methyl-5,6-dihydro-4H-dibenzo[de,g]quinoline

Guidance literature:: With palladium 10% on activated carbon; In acetonitrile; Overall yield = 10.6 g; Reflux;

Reference yield:

: 98-80-6
phenylboronic acid

: 18605-43-1
10,11-dimethoxy-6-methyl-5,6-dihydro-4H-dibenzo[de,g]quinoline

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / K₂CO₃ / Pd(PPh₃)4 / 1,2-dimethoxy-ethane; H₂O / 18 h / Heating

2: 92 percent / NaCN / methanol / 2 h / 60 °C

3: 43 percent / SnCl₄ / CH₂Cl₂ / 24 h / 60 °C

4: BH₃*THF / 5 h / Heating

With borane-THF; sodium cyanide; tin(IV) chloride; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; 1,2-dimethoxyethane; dichloromethane; water; 1: Suzuki cross-coupling reaction;
DOI:10.1016/j.tet.2004.05.014

Reference yield:

: 2-bromo-3,4-dimethoxyphenylacetic acid methyl ester

: 18605-43-1
10,11-dimethoxy-6-methyl-5,6-dihydro-4H-dibenzo[de,g]quinoline

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / K₂CO₃ / Pd(PPh₃)4 / 1,2-dimethoxy-ethane; H₂O / 18 h / Heating

2: 92 percent / NaCN / methanol / 2 h / 60 °C

3: 43 percent / SnCl₄ / CH₂Cl₂ / 24 h / 60 °C

4: BH₃*THF / 5 h / Heating

With borane-THF; sodium cyanide; tin(IV) chloride; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; 1,2-dimethoxyethane; dichloromethane; water; 1: Suzuki cross-coupling reaction;
DOI:10.1016/j.tet.2004.05.014