BENZYL-N,N,N',N'-TETRAISOPROPYLPHOSPHORAMIDITE

Base Information

• Chemical Name: BENZYL-N,N,N',N'-TETRAISOPROPYLPHOSPHORAMIDITE
• CAS No.: 53617-91-7
• Molecular Formula: C19H35N2P
• Molecular Weight: 226.258
• Mol file: 53617-91-7.mol

Synonyms:BENZYL-N,N,N',N'-TETRAISOPROPYLPHOSPHORAMIDITE

Chemical Property of BENZYL-N,N,N',N'-TETRAISOPROPYLPHOSPHORAMIDITE

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BENZYL-N,N,N',N'-TETRAISOPROPYLPHOSPHORAMIDITE

There total 3 articles about BENZYL-N,N,N',N'-TETRAISOPROPYLPHOSPHORAMIDITE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N,N,N,N,N-hexamethylphosphoric triamide (680-31-9) + benzyl alcohol (100-51-6,185532-71-2) → C11H19N2OP (53617-91-7)

Guidance literature:

Multistep reaction; (i) PCl₃, (ii) /BRN= 878307/, Et₂O, Et₃N;

DOI:10.1021/ja00825a034

Reference yield:

bis(N,N-dimethylamino)chlorophosphine (3348-44-5) + benzyl alcohol (100-51-6,185532-71-2) → C11H19N2OP (53617-91-7)

Guidance literature:

With triethylamine;

DOI:10.1039/c39750000612

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) + Hexamethylphosphorous triamide (1608-26-0) → C11H19N2OP (53617-91-7)

Guidance literature:

In 1,4-dioxane; for 42h;

DOI:10.1134/S1070363206020046

upstream raw materials:

N,N,N,N,N,N-hexamethylphosphoric triamide

benzyl alcohol

bis(N,N-dimethylamino)chlorophosphine

Hexamethylphosphorous triamide

Downstream raw materials:

2,2,2-trichloroethylbenzene

benzyl chloride

ethyl 2,2-dichloro-3-phenylpropionate

α,α-dichlorobibenzyl