Isoquinoline, 4-broMo-1,7-dichloro-

Base Information Edit

Chemical Name:Isoquinoline, 4-broMo-1,7-dichloro-
CAS No.:953421-74-4
Molecular Formula:C9H4BrCl2N
Molecular Weight:276.947
Hs Code.:
Mol file:953421-74-4.mol

Synonyms:Isoquinoline, 4-broMo-1,7-dichloro-;4-bromo-1,7-dichloroIsoquinoline

Suppliers and Price of Isoquinoline, 4-broMo-1,7-dichloro-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-1,7-dichloro-isoquinoline
10mg
$ 75.00

J&W Pharmlab
4-Bromo-1,7-dichloro-isoquinoline 97%
100mg
$ 212.00

Total 7 raw suppliers

Chemical Property of Isoquinoline, 4-broMo-1,7-dichloro- Edit

Chemical Property:

PSA：12.89000
LogP:4.30410

Purity/Quality:

NLT 98% ^*data from raw suppliers

4-Bromo-1,7-dichloro-isoquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4-Bromo-1,7-dichloro-isoquinoline acts as a reagent in the discovery of Asunaprevir (BM-650032), an inhibitor of NS3 Protease for hepatitis C virus infection.

Technology Process of Isoquinoline, 4-broMo-1,7-dichloro-

There total 12 articles about Isoquinoline, 4-broMo-1,7-dichloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1028252-13-2
4-bromo-7-chloroisoquinolin-1-ol

: 953421-74-4
4-bromo-1,7-dichloroisoquinoline

Guidance literature:: With trichlorophosphate; for 5h; Reflux; Inert atmosphere;
DOI:10.1021/jm500297k

Reference yield:

: 953421-73-3
4-bromo-7-chloroisoquinoline 2-oxide

: 953421-74-4
4-bromo-1,7-dichloroisoquinoline

Guidance literature:: 4-bromo-7-chloroisoquinoline 2-oxide; With trichlorophosphate; In chloroform; at 66 ℃; for 3h; Heating / reflux;

With sodium hydrogencarbonate; In chloroform; water; ethyl acetate;

Reference yield:

: 1028252-13-2
4-bromo-7-chloro-2H-isoquinolin-1-one

: 953421-74-4
4-bromo-1,7-dichloroisoquinoline

Guidance literature:: 4-bromo-7-chloro-2H-isoquinolin-1-one; With trichlorophosphate; for 5h; Reflux;

With sodium hydroxide; In dichloromethane; at -35 ℃; pH=8;