Base Information
Edit
- Chemical Name:Hydron;pyridine
- CAS No.:16969-45-2
- Molecular Formula:C5H6N+
- Molecular Weight:80.1093
- Hs Code.:
- Mol file:16969-45-2.mol
Synonyms:
Synonyms:
99% *data from raw suppliers
There total 19 articles about Hydron;pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
Reference yield:
Reference yield:
Reference yield:
The research focuses on the transformation of pyridiniums derived from amino alcohols and diamines, aiming to explore novel ring closures and the synthesis of various heterocycles. The study demonstrates that pyridiniums formed from amino alcohols can cyclize to ethers or rearrange to aldehydes upon heating, while those derived from diamines can be acylated or converted into ureas or thioureas, leading to the formation of dihydro-thiazoles, thiazines, and oxazoles. Key chemicals utilized in the process include 2,4,6-triphenylpyrylium perchlorate, tetrafluoroborate, and various amino alcohols such as ethanolamine and hydroxypropylamines, as well as diamines like 1,6-diaminohexane. The findings suggest that intramolecular nucleophilic attack is a viable method for synthesizing diverse functional groups, highlighting the versatility of pyridinium salts in organic synthesis.
The research aims to develop a practical method for the optical resolution of racemic alcohols or esters through lipase-catalyzed transformation followed by sulfation. The method involves converting racemic alcohols or esters into optically active alcohols and esters using lipase, then treating the resulting mixtures with sulfur dioxide pyridine complex to form esters and pyridinium salts of monoalkyl sulfates. These mixtures are then diluted with hydrophobic solvents like diisopropyl ether and washed with water to separate the esters. The procedure is advantageous for large-scale production as it avoids the need for laborious column chromatography. The study concludes that this method is widely applicable, yielding high enantiomer excesses and high purity esters with alcohol content kept below 1%. The optically active esters obtained can be easily converted back to alcohols by acid- or base-catalyzed hydrolysis, making the procedure suitable for synthesizing a variety of optically active alcohols.
The research investigates the primary kinetic isotope effects (KIE) for hydride transfer reactions between NAD+ analogues (pyridinium, quinolinium, phenanthridinium, and acridinium ions) and 1,3-dimethyl-2-phenylbenzimidazoline in a 4:1 mixture of 2-propanol and water at 25 °C. The study finds that the KIE values systematically vary from 6.27 to 4.06 as the equilibrium constant changes from around 10 to 10^12. This variation is consistent with Marcus theory, which assumes no high-energy intermediates and suggests that the perpendicular effect, arising from changes in bond distances and orders in critical complexes, is primarily responsible for the observed changes in KIE. The parallel effect (Leffler-Hammond effect) contributes less due to the high intrinsic barrier. The study supports Marcus theory's applicability to hydride transfer reactions and highlights the significant role of corner-cutting tunneling in hydrogen transfer reactions.
Total 8 Pictures about this product
