6-Benzoyl-5,7-dihydroxy-2,2-diMethylchroMane

Base Information

• Chemical Name: 6-Benzoyl-5,7-dihydroxy-2,2-diMethylchroMane
• CAS No.: 86606-14-6
• Molecular Formula: C18H18O4
• Molecular Weight: 298.33312
• Mol file: 86606-14-6.mol

Synonyms:6-Benzoyl-5,7-dihydroxy-2,2-diMethylchroMane;(5,7-Dihydroxy-2,2-diMethylchroMan-6-yl)(phenyl)Methanone

Chemical Property of 6-Benzoyl-5,7-dihydroxy-2,2-diMethylchroMane

Chemical Property:

• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

6-Benzoyl-5,7-Dihydroxy-2,2-Dimethylchromane 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Benzoyl-5,7-dihydroxy-2,2-diMethylchroMane

There total 1 articles about 6-Benzoyl-5,7-dihydroxy-2,2-diMethylchroMane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 7.0%

2-benzoylphloroglucinol (3555-86-0) + isoprene (78-79-5,9003-31-0) → 8-Benzoyl-5,7-dihydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran (63565-07-1) + 6-Benzoyl-5,7-dihydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran (86606-14-6) + 6-Benzoyl-5-hydroxy-2,2,8,8-tetramethyl-3,4,9,10-tetrahydro-2H,8H-benzo<1,2-b:3,4-b'>dipyran (83611-02-3)

Guidance literature:

With phosphoric acid; In xylene; at 30 - 35 ℃; for 12h;

DOI:10.1055/s-1983-30356

Reference yield: 95.0%

acetic anhydride (108-24-7) + 6-Benzoyl-5,7-dihydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran (86606-14-6) → 5,7-Diacetoxy-6-benzoyl-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran (86606-16-8)

Guidance literature:

DOI:10.1055/s-1983-30356

Reference yield:

6-Benzoyl-5,7-dihydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran (86606-14-6) → 6-Benzoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran (86606-17-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent

2: NBS, benzoyl peroxide / CCl₄ / 24 h / Heating

3: NaOH / ethanol / 1 h / Ambient temperature

With sodium hydroxide; N-Bromosuccinimide; Perbenzoic acid; In tetrachloromethane; ethanol;

DOI:10.1055/s-1983-30356

upstream raw materials:

2-benzoylphloroglucinol

isoprene

Downstream raw materials:

5,7-Diacetoxy-6-benzoyl-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran

6-Benzoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran