N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSINE

Base Information

Chemical Name:N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSINE
CAS No.:111902-68-2
Molecular Formula:C₁₄H₁₉N₅O₄
Molecular Weight:321.336
Hs Code.:
Mol file:111902-68-2.mol

Synonyms:N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSINE;N2-(DMF)-7-DEAZA-2'-DEOXYGUANOSINE

Suppliers and Price of N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N2-(DMF)-7-DEAZA-2'-DEOXYGUANOSINE 95.00%
5MG
$ 500.64

Total 6 raw suppliers

Chemical Property of N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSINE

Chemical Property:

PKA:11.19±0.20(Predicted)
PSA：115.97000
Density:1.56±0.1 g/cm3(Predicted)
LogP:-0.41330

Purity/Quality:

97% ^*data from raw suppliers

N2-(DMF)-7-DEAZA-2'-DEOXYGUANOSINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSINE

There total 1 articles about N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 86392-75-8
7-deaza-2'-deoxyguanosine

: 1188-33-6
N,N-dimethylformamide diethyl diacetal

: 111902-68-2
7-(2-Desoxy-β-D-erythro-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on

Guidance literature:: In N,N-dimethyl-formamide; at 50 ℃; for 1h;

Reference yield: 84.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 111902-68-2
7-(2-Desoxy-β-D-erythro-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on

: 111869-42-2
7-<2-Desoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-erythro-pentofuranosyl>-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In pyridine; for 3h; Ambient temperature;

Reference yield:

: 111902-68-2
7-(2-Desoxy-β-D-erythro-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on

: 111869-43-3
7-<2-Desoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-3-O-(phenoxythiocarbonyl)-β-D-erythro-pentofuranosyl>-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / Huenig base / pyridine / 3 h / Ambient temperature

2: 92 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 16 h / Ambient temperature

With dmap; N-ethyl-N,N-diisopropylamine; In pyridine; dichloromethane;