111869-42-2

Basic information

• Product Name: 5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE
• Synonyms: 5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE;5'-O-(DMT)-N2-(DMF)-7-DEAZA-2'-DEOXYGUANOSINE
• CAS NO: 111869-42-2
• Molecular Formula: C₃₅H₃₇N₅O₆
• Molecular Weight: 623.7
• Mol File: 111869-42-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.29±0.1 g/cm3(Predicted)
• PKA: 11.19±0.20(Predicted)
• CAS DataBase Reference: 5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE(111869-42-2)
• EPA Substance Registry System: 5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE(111869-42-2)

Safety Data

• Hazardous Substances Data: 111869-42-2(Hazardous Substances Data)

Upstream product

• 86392-75-8 7-deaza-2'-deoxyguanosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 111902-68-2 7-(2-Desoxy-β-D-erythro-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on 

Downstream Products

• 111869-44-4 7-(2,3-Didesoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-glycero-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on 
• 111869-49-9 2-amino-7-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-7H-pyrrolo<2,3-d>pyrimidin-4(3H)-one 
• 111869-43-3 7-<2-Desoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-3-O-(phenoxythiocarbonyl)-β-D-erythro-pentofuranosyl>-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on 

Relevant articles and documents

Synthesis of 7-Deaza-2',3'-dideoxyguanosine by Deoxygenation of Its 2'-Deoxy-β-D-ribofuranoside

7-Deaza-2',3'-dideoxyguanosine (4) was prepared by Barton deoxygenation from 7-deaza-2'-deoxyguanosine (1).Protection of the 5'-hydroxy group was accomplished by the 4,4'-dimethoxytriphenylmethyl residue.The 2-amino function was protected either with the same group or the dimethylaminomethylene residue.Assignment of 1H- and 13C-NMR signals of the 2',3'-dideoxy-β-D-glycero-pentofuranosyl moiety of 4 was made on the basis of 2D-NMR spectra.In contrast to 2',3'-dideoxyguanosine compound 4 has an extremely stable N-glycosylic bond towards proton-catalyzed hydrolysis.