Benzyl 2-[(1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl]pyrrolidine-1-carboxylate

Base Information

Chemical Name:Benzyl 2-[(1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl]pyrrolidine-1-carboxylate
CAS No.:127861-61-4
Molecular Formula:C22H25N3O4
Molecular Weight:395.458
Hs Code.:
European Community (EC) Number:668-882-5
Mol file:127861-61-4.mol

Synonyms:Z-PRO-PHE-NH2;127861-61-4

Suppliers and Price of Benzyl 2-[(1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl]pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzyl 2-[(1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl]pyrrolidine-1-carboxylate

Chemical Property:

PSA：101.73000
LogP:3.02950
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:395.18450629
Heavy Atom Count:29
Complexity:570

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)N

Technology Process of Benzyl 2-[(1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl]pyrrolidine-1-carboxylate

There total 4 articles about Benzyl 2-[(1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl]pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 17350-17-3
(S)-2-[(S)-1-(benzyloxycarbonyl)pyrrolidine-2-carboxamido]-3-phenylpropanoic acid

: 127861-61-4
N-(1-benzyloxycarbonyl-L-prolyl)-L-phenylalanin-amide

Guidance literature:: With pyridine; di-tert-butyl dicarbonate; ammonium bicarbonate; In 1,4-dioxane; 4-16 h;
DOI:10.1016/0040-4039(95)01412-B

Reference yield:

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 127861-61-4
N-(1-benzyloxycarbonyl-L-prolyl)-L-phenylalanin-amide

Guidance literature:: With triethylamine; toluene; isobutyl chloroformate; anschliessend Behandeln mit L-Phenylalanin-aethylester und Behandeln des Reaktionsprodukts mit NH₃ in Methanol;