Benzoic acid, 5-chloro-2-(3-oxopropyl)-

Base Information

Chemical Name:Benzoic acid, 5-chloro-2-(3-oxopropyl)-
CAS No.:133772-44-8
Molecular Formula:C10H9ClO3
Molecular Weight:212.633
Hs Code.:
Mol file:133772-44-8.mol

Synonyms:Benzoic acid, 5-chloro-2-(3-oxopropyl)-

Suppliers and Price of Benzoic acid, 5-chloro-2-(3-oxopropyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzoic acid, 5-chloro-2-(3-oxopropyl)-

Chemical Property:

Vapor Pressure:2.2E-05mmHg at 25°C
Boiling Point:346.3°C at 760 mmHg
Flash Point:163.2°C
PSA：54.37000
Density:1.324g/cm³
LogP:2.16970

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 5-chloro-2-(3-oxopropyl)-

There total 4 articles about Benzoic acid, 5-chloro-2-(3-oxopropyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 201230-82-2
carbon monoxide

: 5-chloro-2-vinylbenzoic acid

: 133772-44-8
5-CHLORO-2-(3-OXOPROPYL)-BENZOIC ACID

Guidance literature:: With dicarbonyl(acetylacotonato)rhodium(I); C₇₅H₅₄N₄O₈P₂; hydrogen; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 24h; under 15001.5 Torr; regioselective reaction; Inert atmosphere; Autoclave;
DOI:10.1002/anie.201209582

Reference yield:

: 27007-53-0
methyl-2-bromo-5-chlorobenzoate

: 133772-44-8
5-CHLORO-2-(3-OXOPROPYL)-BENZOIC ACID

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate; palladium dichloride; triphenylphosphine / tetrahydrofuran; water / 0.4 h / 85 °C / Inert atmosphere; Schlenk technique

2: lithium hydroxide / methanol; tetrahydrofuran; water / 70 °C / Inert atmosphere; Schlenk technique

3: N-ethyl-N,N-diisopropylamine; hydrogen; dicarbonyl(acetylacotonato)rhodium(I); C₇₅H₅₄N₄O₈P₂ / dichloromethane / 24 h / 20 °C / 15001.5 Torr / Inert atmosphere; Autoclave

With dicarbonyl(acetylacotonato)rhodium(I); C₇₅H₅₄N₄O₈P₂; hydrogen; caesium carbonate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; palladium dichloride; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1002/anie.201209582

Reference yield:

: 131001-88-2
methyl 2-ethenyl-5-chlorobenzoate

: 133772-44-8
5-CHLORO-2-(3-OXOPROPYL)-BENZOIC ACID

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hydroxide / methanol; tetrahydrofuran; water / 70 °C / Inert atmosphere; Schlenk technique

2: N-ethyl-N,N-diisopropylamine; hydrogen; dicarbonyl(acetylacotonato)rhodium(I); C₇₅H₅₄N₄O₈P₂ / dichloromethane / 24 h / 20 °C / 15001.5 Torr / Inert atmosphere; Autoclave

With dicarbonyl(acetylacotonato)rhodium(I); C₇₅H₅₄N₄O₈P₂; hydrogen; N-ethyl-N,N-diisopropylamine; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1002/anie.201209582