tert-Butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate

Base Information

Chemical Name:tert-Butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate
CAS No.:1223573-53-2
Molecular Formula:C₁₀H₁₇NO₂S
Molecular Weight:215.316
Hs Code.:2934999090
Mol file:1223573-53-2.mol

Synonyms:tert-Butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate

Suppliers and Price of tert-Butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Apolloscientific
tert-Butyl1-thia-6-azaspiro[3.3]heptane-6-carboxylate
250mg
$ 1010.00

American Custom Chemicals Corporation
TERT-BUTYL-1-THIA-6-AZASPIRO-[3.3]-HEPTANE-6-CARBOXYLATE 95.00%
5MG
$ 499.77

Total 8 raw suppliers

Chemical Property of tert-Butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate

Chemical Property:

PSA：54.84000
LogP:2.05070

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl1-thia-6-azaspiro[3.3]heptane-6-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-Butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate

There total 4 articles about tert-Butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 1223573-24-7
tert-butyl 3-(2-hydroxyethyl)-3-mercaptoazetidine-1-carboxylate

: 1223573-53-2
tert-butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate

Guidance literature:: With diethoxyltriphenylphosphorane; In toluene; at -30 - 20 ℃; for 13h; Inert atmosphere;
DOI:10.1021/ol1003302

Reference yield:

: 398489-26-4
tert-butyl 3-oxoazetidine-1-carboxylate

: 1223573-53-2
tert-butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: dichloromethane / 40 °C

2: piperidine / tetrahydrofuran / 20 °C

3: lithium aluminium tetrahydride / diethyl ether / 20 °C / Cooling with ice

4: diethoxyltriphenylphosphorane / toluene / -30 - 20 °C / Inert atmosphere

With piperidine; lithium aluminium tetrahydride; diethoxyltriphenylphosphorane; In tetrahydrofuran; diethyl ether; dichloromethane; toluene;

Reference yield:

: 1223573-23-6
tert-butyl 3-(2-oxomethylene)azetidine-1-carboxylic acid

: 1223573-53-2
tert-butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: piperidine / tetrahydrofuran / 20 °C

2: lithium aluminium tetrahydride / diethyl ether / 20 °C / Cooling with ice

3: diethoxyltriphenylphosphorane / toluene / -30 - 20 °C / Inert atmosphere

With piperidine; lithium aluminium tetrahydride; diethoxyltriphenylphosphorane; In tetrahydrofuran; diethyl ether; toluene;