1-Thia-6-aza-spiro[3.3]heptane-1,1-dioxide

Base Information

Chemical Name:1-Thia-6-aza-spiro[3.3]heptane-1,1-dioxide
CAS No.:1352546-75-8
Molecular Formula:C5H9NO2S
Molecular Weight:147.198
Hs Code.:2933990090
Mol file:1352546-75-8.mol

Synonyms:1-Thia-6-aza-spiro[3.3]heptane-1,1-dioxide;1-THIA-6-AZASPIRO[3.3]HEPTANE 1,1-DIOXIDE HYDROCHLORIDE

Suppliers and Price of 1-Thia-6-aza-spiro[3.3]heptane-1,1-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Thia-6-azaspiro[3.3]heptane 1,1-dioxide hydrochloride 95+%
250mg
$ 1393.00

Matrix Scientific
1-Thia-6-azaspiro[3.3]heptane 1,1-dioxide hydrochloride 95+%
1g
$ 3696.00

Crysdot
1-Thia-6-azaspiro[3.3]heptane1,1-dioxide 97%
1g
$ 2567.00

American Custom Chemicals Corporation
1-THIA-6-AZASPIRO-[3.3]-HEPTANE-1,1-DIOXIDE HYDROCHLORIDE 95.00%
5MG
$ 501.00

Total 11 raw suppliers

Chemical Property of 1-Thia-6-aza-spiro[3.3]heptane-1,1-dioxide

Chemical Property:

Boiling Point:377.6±35.0 °C(Predicted)
PKA:7.12±0.20(Predicted)
PSA：54.55000
Density:1.44
LogP:1.35850

Purity/Quality:

97% ^*data from raw suppliers

1-Thia-6-azaspiro[3.3]heptane 1,1-dioxide hydrochloride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Thia-6-aza-spiro[3.3]heptane-1,1-dioxide

There total 5 articles about 1-Thia-6-aza-spiro[3.3]heptane-1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1223573-25-8
tert-butyl 1-thia-6-azaspiro[3.3]heptane-6-carboxylate 1,1-dioxide

: 1352546-75-8
1-thia-6-azaspiro[3.3]heptane-1,1-dioxide

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 18h;

Reference yield:

: 1223573-23-6
tert-butyl 3-(2-oxomethylene)azetidine-1-carboxylic acid

: 1352546-75-8
1-thia-6-azaspiro[3.3]heptane-1,1-dioxide

Guidance literature:: Multi-step reaction with 5 steps

1: piperidine / tetrahydrofuran / 6 h / 20 °C

2: lithium aluminium tetrahydride / diethyl ether / 0.42 h / 20 °C

3: diethoxyltriphenylphosphorane / toluene / 13 h / -30 - 20 °C

4: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3.75 h / 0 - 20 °C

5: hydrogenchloride / 1,4-dioxane / 18 h / 20 °C

With piperidine; hydrogenchloride; lithium aluminium tetrahydride; diethoxyltriphenylphosphorane; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane; toluene;

Reference yield:

: 1223573-52-1
tert-butyl 3-(acetylsulfanyl)-3-(2-oxoethyl)azetidine-1-carboxylate

: 1352546-75-8
1-thia-6-azaspiro[3.3]heptane-1,1-dioxide

Guidance literature:: Multi-step reaction with 4 steps

1: lithium aluminium tetrahydride / diethyl ether / 0.42 h / 20 °C

2: diethoxyltriphenylphosphorane / toluene / 13 h / -30 - 20 °C

3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3.75 h / 0 - 20 °C

4: hydrogenchloride / 1,4-dioxane / 18 h / 20 °C

With hydrogenchloride; lithium aluminium tetrahydride; diethoxyltriphenylphosphorane; 3-chloro-benzenecarboperoxoic acid; In 1,4-dioxane; diethyl ether; dichloromethane; toluene;