2-Cyclohexen-1-one,5-(hydroxymethyl)-3-methoxy-5-methyl-(9CI)

Base Information

Chemical Name:2-Cyclohexen-1-one,5-(hydroxymethyl)-3-methoxy-5-methyl-(9CI)
CAS No.:615580-90-0
Molecular Formula:C9H14O3
Molecular Weight:170.21
Hs Code.:
Mol file:615580-90-0.mol

Synonyms:2-Cyclohexen-1-one,5-(hydroxymethyl)-3-methoxy-5-methyl-(9CI)

Suppliers and Price of 2-Cyclohexen-1-one,5-(hydroxymethyl)-3-methoxy-5-methyl-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-Cyclohexen-1-one,5-(hydroxymethyl)-3-methoxy-5-methyl-(9CI)

Chemical Property:

PSA：46.53000
LogP:0.87820

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Cyclohexen-1-one,5-(hydroxymethyl)-3-methoxy-5-methyl-(9CI)

There total 1 articles about 2-Cyclohexen-1-one,5-(hydroxymethyl)-3-methoxy-5-methyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 126395-81-1
methyl 3-methoxy-1-methyl-5-oxocyclohex-3-ene-1-carboxylate

: 615580-90-0
5-hydroxymethyl-3-methoxy-5-methyl-2-cyclohexen-1-one

Guidance literature:: methyl 3-methoxy-1-methyl-5-oxocyclohex-3-ene-1-carboxylate; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 - -15 ℃; for 0.5h;

With diisobutylaluminium hydride; In tetrahydrofuran; hexane; toluene; at -78 - 20 ℃;
DOI:10.1016/j.tet.2005.07.017

Reference yield: 91.0%

: 615580-90-0
5-hydroxymethyl-3-methoxy-5-methyl-2-cyclohexen-1-one

: 18162-48-6
tert-butyldimethylsilyl chloride

: 615580-91-1
5-t-butyldimethylsilyloxymethyl-3-methoxy-5-methyl-2-cyclohexen-1-one

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.tet.2005.07.017

Reference yield:

: 615580-90-0
5-hydroxymethyl-3-methoxy-5-methyl-2-cyclohexen-1-one

: (5SR,6RS)-6-(2'-butenyl)-5-t-butyldimethylsilyloxymethyl-3-methoxy-5-methyl-2-cyclohexen-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: 91 percent / dimethylformamide / 20 °C

2.1: n-BuLi; (i-Pr)2NH / hexane; tetrahydrofuran / 0.5 h / -78 - -15 °C

2.2: tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / 0.5 h / -15 - 20 °C

With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2005.07.017