()-11-nor-9-carboxy-Δ9-THC-d3 (solution)

Base Information

Chemical Name:()-11-nor-9-carboxy-Δ9-THC-d3 (solution)
CAS No.:130381-15-6
Molecular Formula:C21H25D3O4
Molecular Weight:347.463105334
Hs Code.:
Mol file:130381-15-6.mol

Synonyms:()-11-nor-9-carboxy-Δ9-THC-d3 (solution)

Suppliers and Price of ()-11-nor-9-carboxy-Δ9-THC-d3 (solution)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
(?)-11-nor-9-carboxy-Δ9-THC-d3 (exempt preparation) ≥99% deuterated forms (d1-d3)
1mg
$ 392.00

Cayman Chemical
(?)-11-nor-9-carboxy-Δ9-THC-d3 (exempt preparation) ≥99% deuterated forms (d1-d3)
500μg
$ 221.00

Cayman Chemical
(?)-11-nor-9-carboxy-Δ9-THC-d3 (exempt preparation) ≥99% deuterated forms (d1-d3)
100μg
$ 49.00

AK Scientific
Unii-0Q7wyx30LC
1mg
$ 629.00

Total 2 raw suppliers

Chemical Property of ()-11-nor-9-carboxy-Δ9-THC-d3 (solution)

Chemical Property:

PSA：66.76000
LogP:4.80050

Purity/Quality:

99% ^*data from raw suppliers

(?)-11-nor-9-carboxy-Δ9-THC-d3 (exempt preparation) ≥99% deuterated forms (d1-d3) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description (?)-11-nor-9-carboxy-Δ9-THC-d3 (exempt preparation) contains three deuterium atoms at the 5 position. It is intended for use as an internal standard for the quantification of (?)-11-nor-9-carboxy-Δ9-THC (exempt preparation) by GC- or LC-mass spectrometry. Δ9-Tetrahydrocannabinol (Δ9-THC), the active constituent of marijuana, is metabolized primarily by hydroxylation at the allylic C-11 position followed by oxidation to (?)-11-nor-9-carboxy-Δ9-THC. (?)-11-nor-9-carboxy-Δ9-THC is the major metabolite of Δ9-THC and is used as an internal standard in various analytical procedures to unequivocally confirm its presence in biological fluids.

Technology Process of ()-11-nor-9-carboxy-Δ9-THC-d3 (solution)

There total 2 articles about ()-11-nor-9-carboxy-Δ9-THC-d3 (solution) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 949595-96-4
C₃₅H₄₉⁽²⁾H₃N₂SO₄

: 124-38-9,18923-20-1
carbon dioxide

: 130381-15-6,136844-96-7
(6aR,10aR)-6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-(5',5',5'-²H₃-pentyl)-6H-dibenzo[b,d]pyran-9-carboxylic acid

: C₂₁H₂₅⁽²⁾H₃O₄

Guidance literature:: C₃₅H₄₉⁽²⁾H₃N₂SO₄; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; at -78 - 0 ℃; for 1.5h;

carbon dioxide; In hexane; at 0 ℃; for 0.166667h; Further stages.;
DOI:10.1016/j.tet.2007.06.006

Reference yield:

: 949595-91-9
(6aR,10aR)-6,6a,7,8,10,10a-hexahydro-1-hydroxy-6,6-dimethyl-3-(5',5',5'-²H₃-pentyl)-9H-dibenzo[b,d]pyran-9-one

: 130381-15-6,136844-96-7
(6aR,10aR)-6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-(5',5',5'-²H₃-pentyl)-6H-dibenzo[b,d]pyran-9-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: benzene / 0.17 h / 40 - 42 °C

2.1: n-butyllithium; N,N,N',N'-tetramethylethylenediamine / hexane / 1.5 h / -78 - 0 °C

2.2: 137 mg / hexane / 0.17 h / 0 °C

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; benzene; 2.1: Shapiro reaction;
DOI:10.1016/j.tet.2007.06.006