Methyl 2-(2-(bromomethyl)phenyl)-2-(methoxyimino)acetate

Base Information

• Chemical Name: Methyl 2-(2-(bromomethyl)phenyl)-2-(methoxyimino)acetate
• CAS No.: 115199-26-3
• Molecular Formula: C11H12BrNO3
• Molecular Weight: 286.125
• European Community (EC) Number: 601-349-7
• Mol file: 115199-26-3.mol

Synonyms:METHYL 2-(2-(BROMOMETHYL)PHENYL)-2-(METHOXYIMINO)ACETATE;115199-26-3;SCHEMBL3621281;LDPXOYHMGOQPIV-JLHYYAGUSA-N;BS-45173;methyl E-2-(bromomethyl)phenylglyoxylate O-methyloxime;methyl (E)-2-(bromomethyl)phenylglyoxylate O-methyloxime;methyl E-2-(bromomethyl)-phenyl-glyoxylate O-methyloxime;Methyl-(E)-2 -(bromomethylphenyl)-2-methoxyiminoacetate;Methyl-(E)-2-(bromomethylphenyl)-2-methoxyiminoacetate;(E)-Methyl-2-(2-bromomethylphenyl)-2-methoxyiminoacetate;methyl-(E)-2-(2-bromomethylphenyl)-2-methoxyiminoacetate;methyl (2Z)-2-[2-(bromomethyl)phenyl]-2-methoxyiminoacetate;(2-bromomethyl-phenyl)-[(E)-methoxyimino]-acetic acid methyl ester

Chemical Property of Methyl 2-(2-(bromomethyl)phenyl)-2-(methoxyimino)acetate

Chemical Property:

• Boiling Point: 343.7±44.0 °C(Predicted)
• PSA: 47.89000
• Density: 1.38±0.1 g/cm3(Predicted)
• LogP: 2.10500
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 285.00006
• Heavy Atom Count: 16
• Complexity: 268

Purity/Quality:

97% ^*data from raw suppliers

2-[2-(Bromomethyl)phenyl]-2-(methoxyimino)aceticAcidMethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C(=NOC)C1=CC=CC=C1CBr
• Isomeric SMILES: COC(=O)/C(=N\OC)/C1=CC=CC=C1CBr

Technology Process of Methyl 2-(2-(bromomethyl)phenyl)-2-(methoxyimino)acetate

There total 3 articles about Methyl 2-(2-(bromomethyl)phenyl)-2-(methoxyimino)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

→ methyl 2-(2-bromomethyl)phenyl-2-methoxyiminoacetate (115199-26-3)

Guidance literature:

With sodium bromate; 2,2'-azobis(isobutyronitrile); sodium hydrogensulfite; In water; ethyl acetate; at 65 - 75 ℃; for 7h;

Reference yield:

methyl 2-methyl-α-methoxyiminophenylacetate (115199-21-8) → methyl 2-(2-bromomethyl)phenyl-2-methoxyiminoacetate (115199-26-3)

Guidance literature:

With Hg; bromine; In tetrachloromethane; water; ethyl acetate;

Reference yield:

methyl 2-(2'-bromomethylphenyl)-2-oxoacetate (126534-57-4) + N-methoxylamine hydrochloride (593-56-6) → methyl 2-(2-bromomethyl)phenyl-2-methoxyiminoacetate (115199-26-3)

Guidance literature:

In methanol; water; ethyl acetate;

upstream raw materials:

methyl 2-methyl-α-methoxyiminophenylacetate

methyl 2-(2'-bromomethylphenyl)-2-oxoacetate

N-methoxylamine hydrochloride

Downstream raw materials:

methyl (2E)-2-[2-[(1,3-dioxoisoindolin-2-yl)oxymethyl]phenyl]-2-methoxyiminoacetate