N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine

Base Information

Chemical Name:N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
CAS No.:476159-98-5
Molecular Formula:C₂₃H₂₇ClN₄O₃
Molecular Weight:442.945
Hs Code.:
European Community (EC) Number:637-153-3
UNII:0361Z8214O
DSSTox Substance ID:DTXSID00197222
Wikidata:Q21547118
NCI Thesaurus Code:C162339
Pharos Ligand ID:Y76TBFV8A1B2
ChEMBL ID:CHEMBL426161
Mol file:476159-98-5.mol

Synonyms:AZM475271;N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine

Suppliers and Price of N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
AZM475271
1mg
$ 110.00

Tocris
AZM475271 ≥99%(HPLC)
10
$ 271.00

Tocris
AZM475271 ≥99%(HPLC)
50
$ 1088.00

DC Chemicals
AZM475271 >98%
1 g
$ 2400.00

DC Chemicals
AZM475271 >98%
250 mg
$ 1200.00

DC Chemicals
AZM475271 >98%
100 mg
$ 600.00

Crysdot
AZM475271 98+%
10mg
$ 111.00

Crysdot
AZM475271 98+%
5mg
$ 76.00

Crysdot
AZM475271 98+%
50mg
$ 444.00

ChemScene
AZM475271 99.94%
50mg
$ 610.00

Total 8 raw suppliers

Chemical Property of N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine

Chemical Property:

Boiling Point:556.1±50.0 °C(Predicted)
PKA:8.92±0.10(Predicted)
PSA：68.74000
Density:1.252±0.06 g/cm3(Predicted)
LogP:4.77550
XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:442.1771684
Heavy Atom Count:31
Complexity:551

Purity/Quality:

99%, ^*data from raw suppliers

AZM475271 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=CC(=C4)OC)Cl)OC
Uses AZM 475271 is an src tyrosine kinase inhibitor.

Technology Process of N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine

There total 1 articles about N-(2-chloro-5-methoxyphenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%